ArticleChinese medical journal2015
Morphological evidence of telocytes in mice aorta.
Article in Chinese medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- Telocytes: history, origin, identification, structure, distribution, and functions.Histochemistry and cell biology · 2025Review
- Distribution characteristics and morphological comparison of telocytes in the aortic bulb and myocardium of yak heart.BMC veterinary research · 2025Article
- A cellular regulator of the niche: telocyte.Tissue barriers · 2023Review
- Telocytes in the human ascending aorta: Characterization and exosome-related KLF-4/VEGF-A expression.Journal of cellular and molecular medicine · 2021Article
- Morpho-functional changes of cardiac telocytes in isolated atrial amyloidosis in patients with atrial fibrillation.Scientific reports · 2021Article
- Role of Podoplanin-Positive Cells in Cardiac Fibrosis and Angiogenesis After Ischemia.Frontiers in physiology · 2021Review
- Myotendinous junction adaptations to ladder-based resistance training: identification of a new telocyte niche.Scientific reports · 2020Article
- Emerging diverse roles of telocytes.Development (Cambridge, England) · 2019Review
- Truncated C-terminus of fibrillin-1 induces Marfanoid-progeroid-lipodystrophy (MPL) syndrome in rabbit.Disease models & mechanisms · 2018Article
- Skin telocytes versus fibroblasts: two distinct dermal cell populations.Journal of cellular and molecular medicine · 2015Article
- Electron microscopy of human fascia lata: focus on telocytes.Journal of cellular and molecular medicine · 2015Article
- Cardiac telocytes are double positive for CD34/PDGFR-α.Journal of cellular and molecular medicine · 2015Article
- Telocytes in regenerative medicine.Journal of cellular and molecular medicine · 2015Review
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTelocytes (TCs) are a novel type of interstitial cells, which have been recently described in a large variety of cavitary and noncavitary organs. TCs have small cell bodies, and remarkably thin, long, and moniliform prolongations called telopodes (Tps). Until now, TCs have been found in various loose connective tissues surrounding the arterioles, venules, and capillaries, but as a histological cellular component, whether TCs exist in large arteries remains unexplored.
methodsTCs were identified by transmission electron microscope in the aortic arch of male C57BL/6 mice.
resultsTCs in aortic arch had small cell bodies (length: 6.06-13.02 μm; width: 1.05-4.25 μm) with characteristics of specific long (7.74-39.05 μm), thin, and moniliform Tps; TCs distributed in the whole connective tissue layer of tunica adventitia: TCs in the innermost layer of tunica adventitia, located at the juncture between media and adventitia, with their long axes oriented parallel to the outer elastic membrane; and TCs in outer layers of tunica adventitia, were embedded among transverse and longitudinal oriented collagen fibers, forming a highly complex three-dimensional meshwork. Moreover, desmosomes were observed, serving as pathways connecting neighboring Tps. In addition, vesicles shed from the surface of TCs into the extracellular matrix, participating in some biological processes.
conclusionsTCs in aorta arch are a newly recognized complement distinct from other interstitial cells in large arteries, such as fibroblasts. And further biologically functional correlations need to be elucidated.
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