Evidence map›Paper›PMID 25646074›Full record

ArticleCurrent genomics2014

Epigenetic modifications due to heavy metals exposure in children living in polluted areas.

Alessandra Bitto, Gabriele Pizzino, Natasha Irrera, Federica Galfo, Francesco Squadrito

Open access · bronzeAbstract read
In one paragraph

Article in Current genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Developmental toxicity of cadmium in infants and children: a review.Environmental analysis, health and toxicology · 2021
    Article
  7. Review
  8. Review
  9. Exposure to arsenite and cadmium induces organotoxicity and miRNAs deregulation in male rats.Environmental science and pollution research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alessandra BittoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Gabriele PizzinoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Natasha IrreraDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Federica GalfoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Francesco SquadritoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
University of Messina · ITAzienda Ospedaliera Universitaria Policlinico "G. Martino" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present article is to provide a summary of the epigenetic modifications that might occur in children exposed to heavy metals pollutants. It is known that children are more susceptible to environmental pollutants, because their detoxification enzymes are less competent, and this may lead to alterations in chromatin structure or of DNA causing, in turn, epigenetic modifications. Little is currently known about the long-term effects of these changes when occur early in childhood, none-theless there are ethics and practical concerns that make the assessment of DNA modifications difficult to perform in large-scale.

Indexed as

ArsenicCadmiumChildren.EpigeneticHeavy metals

Identifiers

PMID25646074
PMCPMC4311390
OpenAlexW2325598638

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.