Evidence map›Paper›PMID 25686609›Full record

ArticleNature2015

Evolution of Darwin's finches and their beaks revealed by genome sequencing.

Sangeet Lamichhaney, Jonas Berglund, Markus Sällman Almén, Khurram Maqbool, Manfred Grabherr, Alvaro Martinez-Barrio, Marta Promerová, Carl-Johan Rubin, Chao Wang, Neda Zamani and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 370 papers.

0numbers the graph read from it
0cells of the map it votes in
370citing papers in PubMed
84.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

370 citing papers in PubMed, 1,050 citations in OpenAlex.

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310 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Sangeet LamichhaneyDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Jonas BerglundDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Markus Sällman AlménDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Khurram MaqboolDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, SE-75007 Uppsala, Sweden.
Manfred GrabherrDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Alvaro Martinez-BarrioDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Marta PromerováDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Carl-Johan RubinDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Chao WangDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Neda Zamani1] Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden [2] Department of Plant Physiology, Umeå University, SE-901 87 Umeå, Sweden.
B Rosemary GrantDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA.
Peter R GrantDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA.
Matthew T WebsterDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.
Leif Andersson1] Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden [2] Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, SE-75007 Uppsala, Sweden [3] Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843-4458, USA.
Uppsala University · SEPrinceton University · USSwedish University of Agricultural Sciences · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Darwin's finches, inhabiting the Galápagos archipelago and Cocos Island, constitute an iconic model for studies of speciation and adaptive evolution. Here we report the results of whole-genome re-sequencing of 120 individuals representing all of the Darwin's finch species and two close relatives. Phylogenetic analysis reveals important discrepancies with the phenotype-based taxonomy. We find extensive evidence for interspecific gene flow throughout the radiation. Hybridization has given rise to species of mixed ancestry. A 240 kilobase haplotype encompassing the ALX1 gene that encodes a transcription factor affecting craniofacial development is strongly associated with beak shape diversity across Darwin's finch species as well as within the medium ground finch (Geospiza fortis), a species that has undergone rapid evolution of beak shape in response to environmental changes. The ALX1 haplotype has contributed to diversification of beak shapes among the Darwin's finches and, thereby, to an expanded utilization of food resources.

Indexed as

Evolution, MolecularAnimalsAvian ProteinsBeakEcuadorFemaleFinchesGene FlowGenomeHaplotypesHybridization, GeneticIndian Ocean IslandsMaleMolecular Sequence DataPhylogenyTranscription FactorsAvian ProteinsTranscription Factors

Identifiers

PMID25686609
OpenAlexW2070534356

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.