Evidence map›Paper›PMID 25739882›Full record

ArticleEuropean journal of heart failure2015

Clinical characteristics, management, and outcomes of acute heart failure patients: observations from the Gulf acute heart failure registry (Gulf CARE).

Kadhim Sulaiman, Prashanth Panduranga, Ibrahim Al-Zakwani, Alawi A Alsheikh-Ali, Khalid F AlHabib, Jassim Al-Suwaidi, Wael Al-Mahmeed, Hussam AlFaleh, Abdelfatah Elasfar, Ahmed Al-Motarreb and 6 more

2 registry-linked trialsAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03658031 phase3unknown statusstarted 2019, after this paper: background citation

Effect of Dapagliflozin on the Progression From Prediabetes to T2DM in Subjects With Myocardial Infarction

Ran2019Enrolled576Registered outcomes1Posted comparisons0ConditionsCVD, Myocardial Infarction, Prediabetes, T2DM (Type 2 Diabetes Mellitus)ArmsDapagliflozin 10mg
PMID 28096223PMID 25425451PMID 28428225PMID 27679584PMID 27814267PMID 24631482PMID 23668478PMID 19490820PMID 17315136PMID 28615237PMID 29227578PMID 16644654other papers from this trial
Open the trial in the graph
NCT03794518 phase3unknown statusnot on this mapstarted 2019, after this paper: background citation

Effect of Combination Therapy With Dapagliflozin Plus Low Dose Pioglitazone on Hospitalization Rate in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction

TypeinterventionalSponsorHamad Medical CorporationRan2019 to 2021Enrolled648ConditionsRisk ReductionArmsPioglitazone Plus dapaglifliozin, Placebo
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kadhim SulaimanDepartment of Cardiology, Royal Hospital, Muscat, Oman.
Prashanth Panduranga
Ibrahim Al-Zakwani
Alawi A Alsheikh-Ali
Khalid F AlHabib
Jassim Al-Suwaidi
Wael Al-Mahmeed
Hussam AlFaleh
Abdelfatah Elasfar
Ahmed Al-Motarreb
Mustafa Ridha
Bassam Bulbanat
Mohammed Al-Jarallah
Nooshin Bazargani
Nidal Asaad
Haitham Amin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe purpose of this study was to describe the clinical characteristics, management, and outcomes of acute heart failure (HF) patients from the Gulf acute heart failure registry (Gulf CARE). METHODS AND

resultsData from 5005 HF patients admitted to 47 hospitals in seven Gulf countries during February to November 2012 were analysed. Fifty-five per cent of patients presented with acute decompensated chronic HF, while 45% had new-onset HF. Mean age was 59 ± 15 years, 63% were males, and 83% were Gulf citizens. Co-morbid conditions were hypertension (61%), diabetes mellitus (50%), CAD (47%), and atrial fibrillation or flutter (14%). The median LVEF was 35% (25-45%) with 69% presenting as HF with reduced EF (HFrEF). CAD was the most prevalent aetiology (53%) followed by idiopathic cardiomyopathy (18%), hypertensive heart disease (16%), and valvular heart disease (9%). At discharge, 71% and 78% of patients received beta-blockers and ACE inhibitors/ARBs, respectively. Use of coronary intervention and device therapy was <10%. In-hospital mortality was 6.3%. Re-hospitalization and cumulative mortality at 3 and 12 months were 18%/13% and 40%/20%, respectively.

conclusionsGulf CARE results show that patients from this region are a decade younger than their Western counterparts, with a high prevalence of diabetes and HFrEF, and a lower prevalence of AF. Use of coronary intervention and device therapy was low, with high re-hospitalization rates. Short- and long-term mortality rates were similar to those of Western registries, but should be interpreted in the light of the younger age of Gulf CARE patients.

Indexed as

RegistriesAdrenergic beta-AntagonistsAdultAgedAge FactorsAngiotensin-Converting Enzyme InhibitorsAtrial FibrillationCoronary Artery DiseaseDiabetes MellitusFemaleHeart FailureHumansHypertensionMaleMiddle AgedMiddle EastAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAcute heart failureHeart failureMiddle EastRegistry

Identifiers

PMID25739882

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.