ArticleHeart and vessels2016
Metabolic syndrome showed significant relationship with carotid atherosclerosis.
Article in Heart and vessels, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 23 citations in OpenAlex.
- Long-term effects of L- and N-type calcium channel blocker on uric acid levels and left atrial volume in hypertensive patients.Heart and vessels · 2016Trial
- Association of metabolic syndrome with carotid atherosclerosis in low-income Chinese individuals: A population-based study.Frontiers in cardiovascular medicine · 2022Article
- Association of risk factors for atherosclerosis, including high-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Carotid Artery Stiffness in Metabolic Syndrome: Sex Differences.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Visceral, general, abdominal adiposity and atherogenic index of plasma in relatively lean hemodialysis patients.BMC nephrology · 2018Article
- The association between gallstone disease and plaque in the abdominopelvic arteries.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Pathological interactions between the endothelin-1 and the angiotensin- converting enzyme among Tunisian coronary patients.BMC cardiovascular disorders · 2016Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic syndrome (MetS) is associated with an increased risk of cardiovascular disease. We assessed the associations between MetS and the indicators of carotid atherosclerosis as assessed by ultrasonography taking into consideration of confounders in the general population. A total of 1281 subjects (856 males, 425 females) were included in the present study. The total plaque score and maximum intima-media thickness (IMT) of the carotid arteries were measured as indicators of atherosclerosis. Cardiovascular risk factors were several metabolic components, serum uric acid, serum C-reactive protein (CRP), and lifestyle factors. MetS was defined according to the criteria of the National Cholesterol Education Program. The prevalences of an elevated total plaque score (≥5) and elevated IMT (>1 mm) of the carotid arteries were significantly higher in subjects with MetS as compared to subjects without MetS. Furthermore, a trend was observed towards higher prevalences of these indicators of atherosclerosis as the number of components of MetS increased. Logistic regression analysis revealed a significant association between elevated plaque score and MetS even after adjustments for age, serum uric acid, serum CRP and lifestyle factors in the males. Among the indicators of atherosclerosis assessed by carotid ultrasonography, a significant independent association was observed between the total plaque score and MetS in males in the general population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.