Evidence map›Paper›PMID 25825596›Full record

ReviewTheranostics2015

Radionuclide imaging of neurohormonal system of the heart.

Xinyu Chen, Rudolf A Werner, Mehrbod S Javadi, Yoshifumi Maya, Michael Decker, Constantin Lapa, Ken Herrmann, Takahiro Higuchi

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Neurohormonal modulation in pulmonary arterial hypertension.The European respiratory journal · 2021
    Review
  5. Cardiac hybrid imaging: novel tracers for novel targets.Journal of geriatric cardiology : JGC · 2021
    Article
  6. Review
  7. Article
  8. Review
  9. NovelACS omega · 2018
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xinyu Chen1. Devision of Nuclear Medicine, University Hospital of Wuerzburg, Wuerzburg, Germany. ; 2. Comprehensive Heart Failure Center, University Hospital of Wuerzburg, Wuerzburg, Germany.
Rudolf A Werner1. Devision of Nuclear Medicine, University Hospital of Wuerzburg, Wuerzburg, Germany. ; 2. Comprehensive Heart Failure Center, University Hospital of Wuerzburg, Wuerzburg, Germany.
Mehrbod S Javadi3. Devision of Nuclear Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD, USA.
Yoshifumi Maya1. Devision of Nuclear Medicine, University Hospital of Wuerzburg, Wuerzburg, Germany.
Michael Decker4. Institute of Pharmacy and Food Chemistry, University of Wuerzburg, Wuerzburg, Germany.
Constantin Lapa1. Devision of Nuclear Medicine, University Hospital of Wuerzburg, Wuerzburg, Germany.
Ken Herrmann1. Devision of Nuclear Medicine, University Hospital of Wuerzburg, Wuerzburg, Germany.
Takahiro Higuchi1. Devision of Nuclear Medicine, University Hospital of Wuerzburg, Wuerzburg, Germany. ; 2. Comprehensive Heart Failure Center, University Hospital of Wuerzburg, Wuerzburg, Germany.
Universitätsklinikum Würzburg · DEJohns Hopkins University · USUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included.

Indexed as

Cardiac-Gated Single-Photon Emission Computer-Assisted TomographyAnimalsHeartHeart FailureHumansNeurosecretory SystemsReceptor, Endothelin ASympathetic Nervous SystemReceptor, Endothelin Acardiac neurohormonal systemHeart failurenuclear cardiologyPETradiotracer.SPECT

Identifiers

PMID25825596
PMCPMC4377725
OpenAlexW2039074056

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.