SynthesisHypertension research : official journal of the Japanese Society of Hypertension2015
Isolated nocturnal hypertension and subclinical target organ damage: a systematic review of the literature.
Synthesis in Hypertension research : official journal of the Japanese Society of Hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Global prevalence of nocturnal hypertension: systematic review and meta-analysis.BMC public health · 2026Pooled it
- Nocturnal Hypertension and Subclinical Cardiac and Carotid Damage: An Updated Review and Meta-Analysis of Echocardiographic Studies.Journal of clinical hypertension (Greenwich, Conn.) · 2016Pooled it
- Exploring the Linear and Non-linear Association Between BMI and Night-Time Blood Pressure Variability.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Review
- The Association Between Premature Ejaculation and Non-Dipper Blood Pressure: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Treatment of Hypertension in Children.Current hypertension reviews · 2024Review
- 7-day Aktiia bracelet vs 24 h ABPM study: more questions than answers?Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Prevalence of Isolated Nocturnal Hypertension and Development of Arterial Stiffness, Left Ventricular Hypertrophy, and Silent Cerebrovascular Lesions: The KoGES (Korean Genome and Epidemiology Study).Journal of the American Heart Association · 2022Article
- Isolated nocturnal hypertension in relation to host and environmental factors and clock genes.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Patients with a Higher Number of Periodic Limb Movements Have Higher Nocturnal Blood Pressure.Journal of clinical medicine · 2022Article
- Isolated Nocturnal Hypertension in Children.Frontiers in pediatrics · 2022Review
- Heart rate turbulence measurements in patients with dipper and non-dipper hypertension: the effects of autonomic functionsTurkish journal of medical sciences · 2021Article
- Prevalence and characteristics of isolated nocturnal hypertension in the general population.The Korean journal of internal medicine · 2021Article
- Isolated nocturnal hypertension is associated with increased left ventricular mass index in children.Pediatric nephrology (Berlin, Germany) · 2021Article
- Assessment of nocturnal hypertension by ambulatory blood pressure monitoring at the forearm in people with morbid obesity.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- The Role of Nocturnal Blood Pressure and Sleep Quality in Hypertension Management.European cardiology · 2020Review
- Blood pressure control and cardiovascular risk profile in hypertensive patients under specialist care in Argentina: Results from the CHARTER study.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Circulating CTRP1 Levels Are Increased and Associated with the STOD in Essential Hypertension in Chinese Patients.Cardiovascular therapeutics · 2019Article
- Seasonal variation in nocturnal home blood pressure fall: the Nagahama study.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Hemoglobin A1c and C-reactive protein are independently associated with blunted nocturnal blood pressure dipping in obesity-related prediabetes.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Isolated nocturnal hypertension (INH) is associated with greater mortality and cardiovascular events. Subclinical target organ damage (TOD) is a prognostic marker for cardiovascular events. Our objective is to systematically summarize evidence on the association between INH and subclinical TOD. Observational population studies were considered. INH was defined as nighttime blood pressure (BP) ⩾120 and/or 70 mm Hg with daytime BP <135/85 mm Hg. We systematically searched Pubmed, EMBASE and the Cochrane Library. Abstracts were reviewed by two assessors. Potentially eligible articles were compared with inclusion criteria. The search yielded 954 titles, 13 abstracts were selected for review and four articles fulfilled inclusion criteria. INH was associated with higher ambulatory arterial stiffness index (0.4 unit vs. 0.35 unit, P<0.05), pulse wave velocity (16.2 m s(-1) vs. 14.7 m s(-1), P<0.05), central (140.4% vs. 134.0%, P<0.05) and peripheral (82.6% vs. 76.5%, P<0.01) augmentation index in a Chinese study. In the same population there was no association with left ventricular hypertrophy documented by electrocardiogram. INH was not associated with increased arterial stiffness or left venticular mass index in a Swedish study. An American study demonstrated higher left ventricular mass (152.46 g vs. 136.16 g, P=0.01) and greater odds of left ventricular hypertrophy (odds ratio 3.03, 95% confidence interval 1.02-9.05) in unadjusted analysis. There was no association with proteinuria. Evidence is inconclusive regarding the association between INH and subclinical TOD. Future research should focus on trying to elucidate the mechanisms that generate INH and contribute to the higher mortality associated with this BP pattern.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.