SynthesisNutrients2015
Role of dietary protein and thiamine intakes on cognitive function in healthy older people: a systematic review.
Synthesis in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Low Protein Intake Is Associated with Frailty in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2018Pooled it
- Relative Protein Intake and Physical Function in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2018Pooled it
- Calanus Oil Supplementation Does Not Further Improve Short-Term Memory or Brain-Derived Neurotrophic Factor in Older Women Who Underwent Exercise Training.Clinical interventions in aging · 2022Trial
- A pilot study of thiamin and folic acid in hemodialysis patients with cognitive impairment.Renal failure · 2021Trial
- Article
- Dietary Adherence and Cognitive Performance in Older Adults by Nativity Status: Results from the National Health and Nutrition Examination Survey (NHANES), 2011-2014.Geriatrics (Basel, Switzerland) · 2024Article
- Meat consumption & positive mental health: A scoping review.Preventive medicine reports · 2024Article
- Dietary consumption of beef and red meat: a scoping review and evidence map on cognitive outcomes across the lifespan.Public health nutrition · 2023Article
- Thiamin (Vitamin BFood & nutrition research · 2023Article
- Protein intake from different sources and cognitive decline over 9 years in community-dwelling older adults.Frontiers in public health · 2022Article
- Article
- Protein Intake and Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis.Nutrition and metabolic insights · 2021Review
- Meat consumption in midlife and risk of cognitive impairment in old age: the Singapore Chinese Health Study.European journal of nutrition · 2020Article
- Article
- Article
- The association between macronutrient intake and cognition in individuals aged under 65 in China: a cross-sectional study.BMJ open · 2018Article
- Enhanced Activities of Blood Thiamine Diphosphatase and Monophosphatase in Alzheimer's Disease.PloS one · 2017Article
- Dietary reference values for thiamin.EFSA journal. European Food Safety Authority · 2016Article
- Hypertrophy-Promoting Effects of Leucine Supplementation and Moderate Intensity Aerobic Exercise in Pre-Senescent Mice.Nutrients · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effectiveness of nutritional interventions to prevent and maintain cognitive functioning in older adults has been gaining interest due to global population ageing. A systematic literature review was conducted to obtain and appraise relevant studies on the effects of dietary protein or thiamine on cognitive function in healthy older adults. Studies that reported on the use of nutritional supplementations and/or populations with significant cognitive impairment were excluded. Seventeen eligible studies were included. Evidence supporting an association between higher protein and/or thiamine intakes and better cognitive function is weak. There was no evidence to support the role of specific protein food sources, such as types of meat, on cognitive function. Some cross-sectional and case-control studies reported better cognition in those with higher dietary thiamine intakes, but the data remains inconclusive. Adequate protein and thiamine intake is more likely associated with achieving a good overall nutritional status which affects cognitive function rather than single nutrients. A lack of experimental studies in this area prevents the translation of these dietary messages for optimal cognitive functioning and delaying the decline in cognition with advancing age.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.