ArticleJournal of diabetes science and technology2015
Rate-of-Change Dependence of the Performance of Two CGM Systems During Induced Glucose Swings.
Article in Journal of diabetes science and technology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Continuous glucose monitoring in patients with type 2 diabetes on hemodialysis.Acta diabetologica · 2021Pooled it
- Accuracy of Real Time Continuous Glucose Monitoring during Different Liquid Solution Challenges in Healthy Adults: A Randomized Controlled Cross-Over Trial.Sensors (Basel, Switzerland) · 2022Trial
- Trial
- Performance of the Freestyle Libre flash glucose monitoring (flash GM) system in individuals with type 1 diabetes: A secondary outcome analysis of a randomized crossover trial.Diabetes, obesity & metabolism · 2019Trial
- Assessing the Accuracy of Continuous Glucose Monitoring (CGM) Calibrated With Capillary Values Using Capillary or Venous Glucose Levels as a Reference.Journal of diabetes science and technology · 2016Trial
- Pediatric Inpatient Continuous Glucose Monitor Accuracy by Sensor Wear Day, Hospital Day, and Glucose Rate of Change.Diabetes technology & therapeutics · 2026Article
- Accuracy and reliability of a continuous glucose monitoring system with a focus on hypoglycaemia.Diabetes, obesity & metabolism · 2026Article
- Scoping Review-Diabetes Technology for Individuals on Kidney Replacement Therapy (Dialysis): Current Trends and Future Directions.Journal of diabetes science and technology · 2025Review
- Accuracy of a continuous glucose monitoring system applied before, during, and after an intense leg-squat session with low- and high-carbohydrate availability in young adults without diabetes.European journal of applied physiology · 2024Article
- Accuracy of a Real-Time Continuous Glucose Monitor in Pediatric Diabetic Ketoacidosis Admissions.Diabetes technology & therapeutics · 2024Article
- Continuous glucose monitoring and intrapersonal variability in fasting glucose.Nature medicine · 2024Article
- Leveraging continuous glucose monitoring for personalized modeling of insulin-regulated glucose metabolism.Scientific reports · 2024Article
- The Impact of Diabetes Education on Continuous Glucose Monitoring in SUS-Dependent Patients in a Northeastern Brazilian City.Life (Basel, Switzerland) · 2024Article
- Enhancement of Ambulatory Glucose Profile for Decision Assistance and Treatment Adjustments.Diagnostics (Basel, Switzerland) · 2024Article
- A probabilistic computation framework to estimate the dawn phenomenon in type 2 diabetes using continuous glucose monitoring.Scientific reports · 2024Article
- Perceptions of Continuous Glucose Monitoring Systems in the T1D Exchange Diabetes Registry: Satisfaction, Concerns, and Areas for Future Improvement.Clinical diabetes : a publication of the American Diabetes Association · 2024Article
- Clinical Performance Evaluation of Continuous Glucose Monitoring Systems: A Scoping Review and Recommendations for Reporting.Journal of diabetes science and technology · 2023Article
- Analytical Performance of the Factory-Calibrated Flash Glucose Monitoring System FreeStyle Libre2Sensors (Basel, Switzerland) · 2023Article
- Pilot study in human healthy volunteers on the use of magnetohydrodynamics in needle-free continuous glucose monitoring.Scientific reports · 2022Article
- Validity of continuous glucose monitoring for categorizing glycemic responses to diet: implications for use in personalized nutrition.The American journal of clinical nutrition · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe accuracy of continuous glucose monitoring (CGM) systems is often assessed with respect to blood glucose (BG) readings. CGM readings are affected by a physiological and a technical time delay when compared to BG readings. In this analysis, the dependence of CGM performance parameters on the BG rate of change was investigated for 2 CGM systems.
methodsData from a previously published study were retrospectively analyzed. An established CGM system (Dexcom G4, Dexcom, San Diego, CA; system A) and a prototype system (Roche Diagnostics GmbH, Mannheim, Germany; system B) with 2 sensors each were worn by 10 subjects in parallel. Glucose swings were induced to achieve rapidly changing BG concentrations. Mean absolute relative differences (MARD) were calculated in different BG rate-of-change categories. In addition, sensor-to-sensor precision was assessed.
resultsAt BG rates of change of -1 mg/dl/min to 0 mg/dl/min and 0 mg/dl/min to +1 mg/dl/min, MARD results were 12.6% and 11.3% for system A and 8.2% and 10.0% for system B. At rapidly changing BG concentrations (<-3 mg/dl/min and ≥+3 mg/dl/min), higher MARD results were found for both systems, but system B was less affected (system A: 24.9% and 29.6%, system B: 10.6% and 16.3%). The impact of rate of change on sensor-to-sensor precision was less pronounced.
conclusionsBoth systems were affected by rapidly changing BG concentrations to some degree, although system B was mostly unaffected by decreasing BG concentrations. It would seem that technological advancements in CGM systems might allow for a more precise tracking of BG concentrations even at rapidly changing BG concentrations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.