ReviewIranian journal of basic medical sciences2014
Cardio-protective and anti-cancer therapeutic potential of Nigella sativa.
Review in Iranian journal of basic medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03175757 (A Randomized, Single-blind, Placebo-controlled Study to Evaluate the Effects of a Turmeric and Black Cumin Seed Formulation on Cholesterol Levels Among Generally Healthy Participants), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized, Single-blind, Placebo-controlled Study to Evaluate the Effects of a Turmeric and Black Cumin Seed Formulation on Cholesterol Levels Among Generally Healthy Participants
Who cites it
23 citing papers in PubMed, 86 citations in OpenAlex.
- The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial.Nutrients · 2024Trial
- Trial
- Investigating the cardioprotective effects ofBiochemistry and biophysics reports · 2025Article
- Functional, Nutraceutical, and Pharmacological Properties of Black Seed.Food science & nutrition · 2025Review
- Diversity of Ethiopian Black Cumin (Biochemistry research international · 2025Article
- Antimicrobial Properties and Therapeutic Potential of Bioactive Compounds inMolecules (Basel, Switzerland) · 2024Review
- Nigella sativa oil attenuates inflammation and oxidative stress in experimental myocardial infarction.BMC complementary medicine and therapies · 2024Article
- Potential Pharmacological Applications ofPlants (Basel, Switzerland) · 2023Review
- Therapeutic benefits of prophetic medicine remedies in treating hematological diseases (A review article).American journal of blood research · 2023Review
- Magnetite-Based Nanostructured Coatings Functionalized withAntibiotics (Basel, Switzerland) · 2022Article
- The Potential Role ofMolecules (Basel, Switzerland) · 2022Article
- Synergistic effect of thymoquinone and nystatin in the treatment of oral candidiasis; an in vitro study.Odontology · 2022Article
- The Role of Bioactive Compounds from Dietary Spices in the Management of Metabolic Syndrome: An Overview.Nutrients · 2021Review
- The Role of Bioactive Compounds ofNutrients · 2021Review
- Review
- Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation andSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- Nigella Sativa Oil Protects the Rat Ovary from Oxidative Injury Due to Ischemia-Reperfusion.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone.Journal of pharmacopuncture · 2017Review
- The effect ofResearch in pharmaceutical sciences · 2017Article
- Anticancer Chemodiversity of Ranunculaceae Medicinal Plants: Molecular Mechanisms and Functions.Current genomics · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nigella sativa is the miraculous plant having a lot of nutritional and medicinal benefits, and attracts large number of nutrition and pharmacological researchers. N. sativa seed composition shows that it is the blessing of nature and it contains and many bioactive compounds like thymoquinone, α-hederin, alkaloids, flavonoids, antioxidants, fatty acids many other compounds that have positive effects on curing of different diseases. Several medicinal properties of N. sativa like its anti-cancer, anti-inflammatory, anti-diabetic, antioxidant activities and many others are well acknowledged. However, this article focuses on activity of N. sativa against cardiovascular diseases and cancer. For gathering required data the authors went through vast number of articles using search engines like Science direct, ELSEVIER, Pub Med, Willey on Line Library and Google scholar and the findings were classified on the basis of relevance of the topic and were reviewed in the article. N. sativa is rich source of different biologically active compounds and is found effective in controlling number of cardiovascular diseases and various cancers both in vivo and in vitro studies.
Indexed as
Identifiers
25859300PMC4387232W1608062055What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.