ArticleJournal of clinical and experimental neuropsychology2015
Glucose regulation and cognitive function after bariatric surgery.
Article in Journal of clinical and experimental neuropsychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Executive Functions in Overweight and Obesity: A Systematic Review of Neuropsychological Cross-Sectional and Longitudinal Studies.Frontiers in psychology · 2019Pooled it
- Obesity in the Workplace: Impact, Outcomes, and Recommendations.Journal of occupational and environmental medicine · 2018Guideline
- Cognitive functioning in adolescents with severe obesity undergoing bariatric surgery or intensive non-surgical treatment in Sweden (AMOS2): a multicentre, open-label, randomised controlled trial.EClinicalMedicine · 2024Article
- Assessment of Cognitive Flexibility in Jordanian Diabetic Patients by Wisconsin Card Sorting and Trail Making Tests: Implications with Demographic, Anthropometric and Therapeutic Variables.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- The relationship between weight loss and cognitive function in bariatric surgery.Surgical endoscopy · 2023Article
- The Effect of Surgical Weight Loss on Cognition in Individuals with Class II/III Obesity.The journal of nutrition, health & aging · 2023Article
- Executive Functioning in Extreme Obesity: Contributions from Metabolic Status, Medical Comorbidities, and Psychiatric Factors.Obesity surgery · 2021Article
- Impact of bariatric surgery on cerebral vascular reactivity and cognitive function: a non-randomized pilot study.Pilot and feasibility studies · 2020Article
- THE EFFECT OF BLOOD GLUCOSE ON QUIET STANDING BALANCE IN YOUNG HEALTHY INDIVIDUALS.Biomedical engineering : applications, basis, and communications · 2020Article
- Visual, Verbal and Everyday Memory 2 Years After Bariatric Surgery: Poorer Memory Performance at 1-Year Follow-Up.Frontiers in psychology · 2020Article
- An insulin resistance associated neural correlate of impulsivity in type 2 diabetes mellitus.PloS one · 2017Article
- Autotaxin is Related to Metabolic Dysfunction and Predicts Alzheimer's Disease Outcomes.Journal of Alzheimer's disease : JAD · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
introductionObesity is associated with cognitive impairment, and bariatric surgery has been shown to improve cognitive functioning. Rapid improvements in glycemic control are common after bariatric surgery and likely contribute to these cognitive gains. We examined whether improvements in glucose regulation are associated with better cognitive function following bariatric surgery.
methodA total of 85 adult bariatric surgery patients underwent computerized cognitive testing and fasting blood draw for glucose, insulin, and glycated hemoglobin (HbA1c) at baseline and 12 months postoperatively.
resultsSignificant improvements in both cognitive function and glycemic control were observed among patients. After controlling for baseline factors, 12-month homeostatic model assessment of insulin resistance HOMA-IR predicted 12-month digits backward (β = -.253, p < .05), switching of attention-A (β = .156, p < .05), and switching of attention-B (β = -.181, p < .05). Specifically, as HOMA-IR decreased over time, working memory, psychomotor speed, and cognitive flexibility improved. Decreases in HbA1c were not associated with postoperative cognitive improvements. After controlling for baseline cognitive test performance, changes in body mass index (BMI) were also not associated with 12-month cognitive function.
conclusionsSmall effects of improved glycemic control on improved aspects of attention and executive function were observed following bariatric surgery among severely obese individuals. Future research is needed to identify the underlying mechanisms for the neurocognitive benefits of these procedures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.