ReviewArchives of gynecology and obstetrics2015
Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery.
Review in Archives of gynecology and obstetrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03219398 (Comparison Effect Between Lower Pressure and Standard Pressure Pneumoperitoneum on Sign of Acute Systemic Inflammation, Endothelial Injury, and Acute Kidney Injury), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison Effect Between Lower Pressure and Standard Pressure Pneumoperitoneum on Sign of Acute Systemic Inflammation, Endothelial Injury, and Acute Kidney Injury: A Randomized Clinical Trial in Living Donor Laparoscopic Nephrectomy
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevention of peritoneal adhesions after gynecological surgery: a systematic review.Archives of gynecology and obstetrics · 2024Pooled it
- Warmed and humidified carbon dioxide for abdominal laparoscopic surgery: meta-analysis of the current literature.Surgical endoscopy · 2017Pooled it
- Warm and humidified insufflation gas during gynecologic laparoscopic surgery reduces postoperative pain in predisposed patients-a randomized, controlled multi-arm trial.Surgical endoscopy · 2022Trial
- Trial
- Prospective, randomized comparison of the use of FloShield Air SystemSurgical endoscopy · 2018Trial
- Laparoscopic Surgery Is Associated With Reduced Small Bowel Obstruction Risk After Colorectal Cancer Surgery: A Nationwide Cohort Study of 5458 Patients.Annals of gastroenterological surgery · 2026Article
- Post-radical hysterectomy ovarian torsion-A gynecological emergency: a case series.Journal of medical case reports · 2024Article
- Application value of machine learning models in predicting intraoperative hypothermia in laparoscopic surgery for polytrauma patients.World journal of clinical cases · 2024Article
- Underneath Images and Robots, Looking Deeper into the Pneumoperitoneum: A Narrative Review.Journal of clinical medicine · 2024Review
- Postsurgical Adhesions: Is There Any Prophylactic Strategy Really Working?Journal of clinical medicine · 2023Review
- An Overview of Postoperative Intraabdominal Adhesions and Their Role on Female Infertility: A Narrative Review.Journal of clinical medicine · 2023Review
- Evaluating the concept of gas‑based intraperitoneal hyperthermia beyond 43˚C in the treatment of peritoneal metastasis: A pilot study.Experimental and therapeutic medicine · 2022Article
- The Effects of Different Pressure Pneumoperitoneum Models Created By Standard or Heated-Humidified COReproductive sciences (Thousand Oaks, Calif.) · 2022Article
- Effects of Heated Pneumoperitoneum on Inflammation, Oxidative Stress, and Peritoneal Histology in Female Dogs That Underwent Video-Assisted Ovariohysterectomy.Veterinary medicine international · 2021Article
- Effects of modified multimodal analgesia on postoperative pain, sedation, and prognosis of gynecological patients.Ibrain · 2021Article
- Modes of carbon dioxide delivery during laparoscopy generate distinct differences in peritoneal damage and hypoxia in a porcine model.Surgical endoscopy · 2020Article
- Hypoxia-Mesenchymal Stem Cells Inhibit Intra-Peritoneal Adhesions Formation by Upregulation of the IL-10 Expression.Open access Macedonian journal of medical sciences · 2019Article
- Physiological effects of partial amniotic carbon dioxide insufflation with cold, dry vs heated, humidified gas in a sheep model.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2019Article
- Experimental study of delivery of humidified-warm carbon dioxide during open abdominal surgery.The British journal of surgery · 2018Article
- Changes in the coelomic microclimate during carbon dioxide laparoscopy: morphological and functional implications.Pleura and peritoneum · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe peritoneum is the serous membrane that covers the abdominal cavity and most of the intra-abdominal organs. It is a very delicate layer highly susceptible to damage and it is not designed to cope with variable conditions such as the dry and cold carbon dioxide (CO2) during laparoscopic surgery. The aim of this review was to evaluate the effects caused by insufflating dry and cold gas into the abdominal cavity after laparoscopic surgery.
methodsA literature search using the Pubmed was carried out. Articles identified focused on the key issues of laparoscopy, peritoneum, morphology, pneumoperitoneum, humidity, body temperature, pain, recovery time, post-operative adhesions and lens fogging.
resultsInsufflating dry and cold CO2 into the abdomen causes peritoneal damage, post-operative pain, hypothermia and post-operative adhesions. Using humidified and warm gas prevents pain after surgery. With regard to hypothermia due to desiccation, it can be fully prevented using humidified and warm gas. Results relating to the patient recovery are still controversial.
conclusionsThe use of humidified and warm insufflation gas offers a significant clinical benefit to the patient, creating a more physiologic peritoneal environment and reducing the post-operative pain and hypothermia. In animal models, although humidified and warm gas reduces post-operative adhesions, humidified gas at 32 °C reduced them even more. It is clear that humidified gas should be used during laparoscopic surgery; however, a question remains unanswered: to achieve even greater clinical benefit to the patient, at what temperature should the humidified gas be when insufflated into the abdomen? More clinical trials should be performed to resolve this query.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.