Evidence map›Paper›PMID 25973282›Full record

ReviewCardiology research and practice2015

Current status of sodium bicarbonate in coronary angiography: an updated comprehensive meta-analysis and systematic review.

Sadeq Ali-Hasan-Al-Saegh, Sadegh Ali-Hassan-Sayegh, Seyed Jalil Mirhosseini, Elham Rahimizadeh, Zahra Ghodratipour, Zahra Sarrafan-Chaharsoughi, Ali Mohammad Dehghan, Mohammad Reza Lotfaliani, Mohammad Rezaeisadrabadi, Elham Kayvanpour and 5 more

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Cardiology research and practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Sadeq Ali-Hasan-Al-Saegh
Sadegh Ali-Hassan-Sayegh *Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Seyed Jalil MirhosseiniCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Elham RahimizadehCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Zahra GhodratipourCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Zahra Sarrafan-ChaharsoughiCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ali Mohammad DehghanCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mohammad Reza LotfalianiCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mohammad RezaeisadrabadiCardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Elham KayvanpourDepartment of Medicine III, University of Heidelberg, Heidelberg, Germany.
Farbod Sedaghat-HamedaniDepartment of Medicine III, University of Heidelberg, Heidelberg, Germany.
Mohamed ZeriouhDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, UK.
Alexander WeymannDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, UK.
Anton SabashnikovDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, UK.
Aron-Frederik PopovDepartment of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, London, UK.
Shahid Sadoughi University of Medical Sciences and Health Services · IRRoyal Brompton & Harefield NHS Foundation Trust · GBHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review with meta-analysis sought to determine comparison of efficacy and safety of hydration with sodium bicarbonate versus sodium chloride on contrast induced nephropathy and clinical outcomes. We searched major electronic databases for studies in randomized controlled trials. A value of P < 0.1 for Q test or I (2) > 50% indicated significant heterogeneity between the studies. Literature search of all databases retrieved 650 studies. 29 studies enrolled in meta-analysis. Pooled analysis indicated about the incidence of CIN (OR of 0.718; 95% CI: 0.60 to 0.85; P = 0.000), requirement of hemodialysis (OR of 1.00; 95% CI: 0.49 to 2.01; P = 0.9), mean changes of serum creatinine (WMD of 2.321; 95% CI: 1.995 to 2.648; P = 0.000), length of hospital stays (WMD of -0.774; 95% CI: -1.65 to 0.10; P = 0.08), major adverse cardiovascular events (OR = 1.075, 95% CI: 0.59 to 1.95; P = 0.8), and mortality (OR of 0.73; 95% CI: 0.42 to 1.26; P = 0.2). Overall, hydration with sodium bicarbonate could significantly reduce CIN and the length of hospital stay compared to sodium chloride. In addition NAC added as a supplement to sodium bicarbonate could increase prophylactic effects against nephropathy.

Identifiers

PMID25973282
PMCPMC4417980
OpenAlexW1982423657

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.