ArticleJournal of experimental botany2015
A geminivirus betasatellite damages the structural and functional integrity of chloroplasts leading to symptom formation and inhibition of photosynthesis.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed, 140 citations in OpenAlex.
- Securing the replication ground: how barley stripe mosaic virus safeguards the host chloroplast envelope.The Plant cell · 2026Article
- SLCMV-Encoded BC1 Protein Suppresses Photosynthesis by Disrupting Chloroplast Structure and Gene Expression.Molecular plant pathology · 2026Article
- RepA Protein of Citrus Chlorotic Dwarf-Associated Virus Impairs Perinuclear Chloroplast Clustering Induced by Lemon Chloroplast Malate Dehydrogenase.Molecular plant pathology · 2025Article
- Article
- DNA Satellites Impact Begomovirus Diseases in a Virus-Specific Manner.International journal of molecular sciences · 2025Review
- Leveraging chlorophyll fluorescence uncovers potato virus Y resistance in potato and its validation through viral quantification and yield loss studies.Plant cell reports · 2025Article
- Differential interactions of ToLCNDV with different betasatellites reveal complex viral dynamics in N. benthamiana.PloS one · 2025Article
- The crucial role of mitochondrial/chloroplast-related genes in viral genome replication and host defense: integrative systems biology analysis in plant-virus interaction.Frontiers in microbiology · 2025Article
- Geminivirus diseases of legumes in India: current status and approaches for management.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Review
- RNA-Seq Analysis and Candidate Gene Mining ofPlants (Basel, Switzerland) · 2024Article
- Stress-related transcriptomic changes associated with GFP transgene expression and active transgene silencing in plants.Scientific reports · 2024Article
- Photosynthetic variation and detoxification strategies based on cadmium uptake, non-protein thiols, and secondary metabolites inWater science and technology : a journal of the International Association on Water Pollution Research · 2024Article
- AmCBF1 activates the expression of GhClpR1 to mediate dark-green leaves in cotton (Gossypium hirsutum).Plant cell reports · 2024Article
- Evidence of microRNAs origination from chloroplast genome and their role in regulating Photosystem II protein N (psbN) mRNA.Biotechnologia · 2024Article
- Integrated transcriptomics, metabolomics and physiological analyses reveal differential response mechanisms of wheat to cadmium and/or salinity stress.Frontiers in plant science · 2024Article
- Geminiviral betasatellites: critical viral ammunition to conquer plant immunity.Archives of virology · 2023Review
- Transcriptome analysis of Citrus limon infected with Citrus yellow vein clearing virus.BMC genomics · 2023Article
- A plant virus protein, NIa-pro, interacts with Indole-3-acetic acid-amido synthetase, whose levels positively correlate with disease severity.Frontiers in plant science · 2023Article
- Plant protection from virus: a review of different approaches.Frontiers in plant science · 2023Review
- NMR-Based Metabolomic Profiling of Mungbean Infected with Mungbean Yellow Mosaic India Virus.Applied biochemistry and biotechnology · 2022Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Geminivirus infection often causes severe vein clearing symptoms in hosts. Recently a betasatellite has emerged as a key regulator of symptom induction. To understand the host-betasatellite interactions in the process of symptom development, a systematic study was carried out involving symptoms induced by a betasatellite associated with radish leaf curl disease (RaLCB) in Nicotiana benthamiana. It has been found that βC1 protein localized to chloroplasts of host cells, and RaLCB lacking βC1, which failed to produce symptoms, had no effect on chloroplast ultrastructure. Vein flecking induced by transiently expressed βC1 was associated with chloroplast ultrastructure. In addition, the betasatellite down-regulates expression of genes involved in chlorophyll biosynthesis as well as genes involved in chloroplast development and plastid translocation. Interestingly, the expression of key host genes involved in chlorophyll degradation remains unaffected. Betasatellite infection drastically reduced the numbers of active reaction centres and the plastoquinol pool size in leaves exhibiting vein clearing symptoms. Betasatellite-mediated impediments at different stages of chloroplast functionality affect the photosynthetic efficiency of N. benthamiana. To the best of the authors' knowledge, this is the first evidence of a chloroplast-targeting protein encoded by a DNA virus which induces vein clearing and structurally and functionally damages chloroplasts in plants.
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