Evidence mapPaperPMID 26153522Full record

ReviewThe international journal of cardiovascular imaging2016

Intravascular ultrasound and optical coherence tomography imaging of coronary atherosclerosis.

Charis Costopoulos, Adam J Brown, Zhongzhao Teng, Stephen P Hoole, Nick E J West, Habib Samady, Martin R Bennett

Abstract readReview
PubMed Publisher
In one paragraph

Review in The international journal of cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Topical issue: multimodality imaging in atherosclerosis.The international journal of cardiovascular imaging · 2016
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charis CostopoulosDivision of Cardiovascular Medicine, University of Cambridge, Level 6, ACCI, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Adam J BrownDivision of Cardiovascular Medicine, University of Cambridge, Level 6, ACCI, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. ajdbrown@me.com.
Zhongzhao TengDepartment of Radiology, University of Cambridge, Cambridge, UK.
Stephen P HooleDepartment of Interventional Cardiology, Papworth Hospital NHS Trust, Cambridge, UK.
Nick E J WestDepartment of Interventional Cardiology, Papworth Hospital NHS Trust, Cambridge, UK.
Habib SamadyDepartment of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Martin R BennettDivision of Cardiovascular Medicine, University of Cambridge, Level 6, ACCI, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. mrb24@medschl.cam.ac.uk.

Funding

British Heart Foundation FS/13/33/30168British Heart Foundation FS/15/26/31441British Heart Foundation RG/13/14/30314Medical Research Council G0800784Medical Research Council G1000847
6 · The paper itself

Abstract

Invasive imaging modalities, in particular intravascular ultrasound (IVUS) and optical coherence tomography (OCT), have become established tools for the in vivo study of coronary atherosclerosis. Their use in clinical studies has confirmed histopathological observations that certain important plaque features, such as thin fibrous caps and large lipid cores, are associated with plaque rupture, the precipitating event for the majority of myocardial infarctions. Serial imaging studies have also successfully been used for the evaluation of potential disease modifying pharmacological agents. Recent prospective IVUS studies have confirmed specific baseline imaging features associated with subsequent adverse clinical outcomes, although absolute event rates were too low for clinical utility. Development of hybrid IVUS-OCT imaging or integration of novel techniques, including near-infrared spectroscopy, plaque structural and endothelial shear stress, have great potential to improve our current ability to identify and stratify atheromatous plaques at risk of rupture.

Indexed as

Plaque, AtheroscleroticTomography, Optical CoherenceUltrasonography, InterventionalCoronary Artery DiseaseCoronary VesselsDisease ProgressionHumansMultimodal ImagingPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsRupture, SpontaneousCoronary atherosclerosisIntravascular ultrasoundOptical coherence tomographyVirtual-histology intravascular ultrasound

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.