Evidence map›Paper›PMID 26308287›Full record

Trial reportThe Journal of asthma : official journal of the Association for the Care of Asthma2016

Efficacy of an in-home test kit in reducing dust mite allergen levels: results of a randomized controlled pilot study.

Amber K Winn, Päivi M Salo, Cynthia Klein, Michelle L Sever, Shawn F Harris, David Johndrow, Patrick W Crockett, Richard D Cohn, Darryl C Zeldin

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of asthma : official journal of the Association for the Care of Asthma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. The Role of Home Environments in Allergic Disease.Clinical reviews in allergy & immunology · 2019
    Review
  4. Review
  5. Bedroom Allergen Exposure Beyond House Dust Mites.Current allergy and asthma reports · 2018
    Review
  6. Review
  7. Article
  8. Indoor allergen exposure and asthma outcomes.Current opinion in pediatrics · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Amber K Winna Division of Intramural Research , National Institute of Environmental Health Sciences, National Institutes of Health , Research Triangle Park , NC , USA .
Päivi M Saloa Division of Intramural Research , National Institute of Environmental Health Sciences, National Institutes of Health , Research Triangle Park , NC , USA .
Cynthia Kleinb Abt Associates , Atlanta , GA , USA .
Michelle L Severc Rho, Inc. , Chapel Hill , NC , USA , and.
Shawn F Harrisd Social & Scientific Systems, Inc. , Durham , NC , USA.
David Johndrowd Social & Scientific Systems, Inc. , Durham , NC , USA.
Patrick W Crockettd Social & Scientific Systems, Inc. , Durham , NC , USA.
Richard D Cohnd Social & Scientific Systems, Inc. , Durham , NC , USA.
Darryl C Zeldina Division of Intramural Research , National Institute of Environmental Health Sciences, National Institutes of Health , Research Triangle Park , NC , USA .
National Institutes of Health · US

Funding

Indoor Allergens And AsthmaZIAES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$8.5M
INDOOR ALLERGENS AND ASTHMAZ01ES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1998 to 2008
$1.9M
Intramural NIH HHS Z01 ES025041NIEHS NIH HHS N01-ES-55553NIEHS NIH HHS Z01-ES025041PHS HHS HHSN291200555553C
6 · The paper itself

Abstract

backgroundDust mite allergens can induce allergic sensitization and exacerbate asthma symptoms. Although dust mite reduction and control strategies exist, few asthmatics employ them.

objectivesWe examined whether an in-home test kit, which quantifies dust mite allergen levels, resulted in behavioral changes in implementation and maintenance of mite reduction strategies and helped reduce allergen levels in homes of dust mite-sensitive children.

methodsWe enrolled 60 households of children aged 5-15 with parent-reported dust mite allergy into a randomized controlled trial. Intervention homes (N = 30) received educational material about reducing dust mites and test kits at 1, 2, 5 and 8 months. Control homes (N = 30) received only educational material. At baseline, 6 and 12 months, study staff visited all homes, collected dust samples from three locations and obtained information about parents' mite reduction behaviors by questionnaire. Allergen concentrations (Der f 2/Der p2) in dust were assessed by immunoassays. After adjusting for visit and location, allergen concentrations in intervention and control homes were compared using mixed effects model analysis.

resultsIn the intervention homes, allergen concentrations in the child's bedroom and living room floors were significantly reduced over time compared to control homes. Although not all location-specific differences in allergen concentrations were statistically significant, combining data across locations, there was a differential reduction in allergen concentrations in the intervention group versus the control group (p = 0.02).

conclusionThe use of in-home test kits along with education may beneficially influence behaviors and attitudes toward dust mite reduction strategies and help reduce residential dust mite allergen levels.

Indexed as

AdolescentAir Pollution, IndoorAllergensAntigens, DermatophagoidesArthropod ProteinsChildChild, PreschoolCysteine EndopeptidasesDustEnvironmental MonitoringHealth EducationHousingHumansPilot ProjectsAllergensAntigens, DermatophagoidesArthropod ProteinsCysteine EndopeptidasesDermatophagoides farinae antigen f 1Dermatophagoides farinae antigen f 2DustD. farinaeD. pteronyssinusdust mite allergenDust mitesindoor allergensintervention trials

Identifiers

PMID26308287
PMCPMC4769118
OpenAlexW1866147486

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.