Evidence map›Paper›PMID 26319606›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2015

Diet, interleukin-17, and childhood asthma in Puerto Ricans.

Yueh-Ying Han, Erick Forno, John M Brehm, Edna Acosta-Pérez, María Alvarez, Angel Colón-Semidey, Winna Rivera-Soto, Hannia Campos, Augusto A Litonjua, John F Alcorn and 2 more

Open access · greenAbstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 4 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. A Multiomics Approach to Identify Genes Associated with Childhood Asthma Risk and Morbidity.American journal of respiratory cell and molecular biology · 2017
    Trial
  6. Article
  7. Dietary Patterns in Relation to Asthma and Wheeze Among Adolescents in a South African Rural Community.International journal of environmental research and public health · 2025
    Article
  8. Foundations of Pediatric Lifestyle Medicine.Children (Basel, Switzerland) · 2025
    Article
  9. Persistent cat ownership and asthma in a longitudinal study of Puerto Rican youth.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Socioeconomic status, diet, and recurrent severe asthma exacerbations in Puerto Rican youth.The journal of allergy and clinical immunology. Global · 2024
    Article
  15. Importance of diet in children and adolescents with obesity and asthma.Pediatric endocrinology, diabetes, and metabolism · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yueh-Ying Han *Division of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA.
Erick Forno *Division of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA.
John M BrehmDivision of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA.
Edna Acosta-PérezBehavioral Sciences Research Institute and Department of Pediatrics, University of Puerto Rico, San Juan, PR.
María AlvarezBehavioral Sciences Research Institute and Department of Pediatrics, University of Puerto Rico, San Juan, PR.
Angel Colón-SemideyBehavioral Sciences Research Institute and Department of Pediatrics, University of Puerto Rico, San Juan, PR.
Winna Rivera-SotoSchool of Public Health, University of Puerto Rico, San Juan, PR.
Hannia CamposHarvard School of Public Health, Boston, MA.
Augusto A LitonjuaChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
John F AlcornDivision of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA.
Glorisa CaninoBehavioral Sciences Research Institute and Department of Pediatrics, University of Puerto Rico, San Juan, PR.
Juan C CeledónDivision of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA.
University of Pittsburgh · USUniversity of Puerto Rico System · PRBrigham and Women's Hospital · USHarvard University · US

Funding

Molecular Basis of Pediatric DiseaseK12HD052892 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TERENCE S. DERMODY · 2007 to 2026
$6.5M
Epigenetic Variation and Childhood Asthma in Puerto RicansR01HL117191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2013 to 2020
$5.8M
Genes, Home Allergens and Asthma Puerto Rican ChildrenR01HL079966 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2006 to 2010
$3.8M
Obesity and Asthma Subphenotypes and Underlying Genetic and Genomic PathwaysK08HL125666 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2015 to 2018
$589k
NHLBI NIH HHS HL079966NHLBI NIH HHS HL117191NHLBI NIH HHS K08 HL125666NHLBI NIH HHS R01 HL079966NHLBI NIH HHS R01 HL117191NICHD NIH HHS HD052892NICHD NIH HHS K12 HD052892
6 · The paper itself

Abstract

backgroundDietary patterns might influence the pathogenesis of asthma in Puerto Ricans, the ethnic group most affected by this disease in the United States.

objectiveTo examine the association among diet, T-helper cell type 17 cytokines, and asthma in Puerto Rican children.

methodsAs part of a case-control study of 678 Puerto Rican children 6 to 14 years old in San Juan, participants completed a 75-item questionnaire on the child's food consumption in the prior week. Foods were aggregated into 7 groups: fruits, vegetables, grains, protein foods, dairy, fats, and sweets. Logistic regression was used to evaluate consumption frequency of each group, plasma T-helper cell type 17 cytokine levels, and asthma. Based on this analysis, a food score (range -2 [unhealthy diet: high consumption of dairy products and sweets, low consumption of vegetables and grains] to +2 [healthy diet: high consumption of grains and vegetables, low consumption of dairy and sweets]) was created to identify dietary patterns.

resultsHigh consumption of grains was associated with lower odds of asthma (adjusted odds ratio [aOR] 0.52, 95% confidence interval [CI] 0.33-0.82), whereas frequent consumption of dairy products (aOR 1.93, 95% CI 1.32-2.84) or sweets (aOR 1.82, 95% CI 1.08-2.72) was associated with higher odds of asthma. A healthier diet (each 1-point increment in food score) was associated with lower levels of interleukin-17F (β = -1.48 pg/mL, 95% CI -1.78 to -1.20) and with 36% decreased odds of asthma (aOR 0.64, 95% CI 0.53-0.77).

conclusionA healthy diet, with frequent consumption of vegetables and grains and low consumption of dairy products and sweets, was associated with lower levels of interleulin-17F and decreased odds of childhood asthma in Puerto Ricans.

Indexed as

Feeding BehaviorAdolescentAsthmaCase-Control StudiesChildDairy ProductsDietEdible GrainFemaleFruitHumansInterleukin-17MalePuerto RicoRisk FactorsSurveys and QuestionnairesIL17F protein, humanInterleukin-17

Identifiers

PMID26319606
PMCPMC4721241
OpenAlexW2114622386

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.