Evidence mapPaperPMID 26423407Full record

ReviewCurrent HIV/AIDS reports2015

Risk of Cardiovascular Disease in an Aging HIV Population: Where Are We Now?

R Martin-Iguacel, J M Llibre, N Friis-Moller

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
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  14. Prevalence and Correlates of Snuff Use, and its Association With Tuberculosis, Among Women Living With HIV in South Africa.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
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  17. Review
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

R Martin-IguacelInfectious Diseases Department, Odense University Hospital, Søndre Boulevard 29, 5000, Odense C, Denmark. raquel@bisaurin.org.
J M LlibreHIV Unit and "Lluita contra la SIDA" Foundation, Hospital Universitari Germans Trias i Pujol. Badalona, Barcelona, Spain. jmllibre.fls.germanstrias@gencat.cat.
N Friis-MollerInfectious Diseases Department, Odense University Hospital, Søndre Boulevard 29, 5000, Odense C, Denmark. Nina.Friis-Moeller@rsyd.dk.
Odense University Hospital · DKFundació Lluita contra les Infeccions · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With more effective and widespread antiretroviral treatment, the overall incidence of AIDS- or HIV-related death has decreased dramatically. Consequently, as patients are aging, cardiovascular disease (CVD) has emerged as an important cause of morbidity and mortality in the HIV population. The incidence of CVD overall in HIV is relatively low, but it is approximately 1.5-2-fold higher than that seen in age-matched HIV-uninfected individuals. Multiple factors are believed to explain this excess in risk such as overrepresentation of traditional cardiovascular risk factors (particularly smoking), toxicities associated with cumulative exposure to some antiretroviral agents, together with persistent chronic inflammation, and immune activation associated with HIV infection. Tools are available to calculate an individual's predicted risk of CVD and should be incorporated in the regular follow-up of HIV-infected patients. Targeted interventions to reduce this risk must be recommended, including life-style changes and medical interventions that might include changes in antiretroviral therapy.

Indexed as

AgingCardiovascular DiseasesEuropeHIV InfectionsHumansRisk FactorsUnited StatesAcute myocardial infarctionAntiretroviral therapyCardiovascular RiskCerebrovascular diseaseHIV

Identifiers

PMID26423407
OpenAlexW2177584147

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.