Evidence map›Paper›PMID 26535929›Full record

ArticleDiabetes technology & therapeutics2015

Evaluation of the Average Daily Risk Range as a Measure of Glycemic Variability in Youths with Type 1 Diabetes.

Susana R Patton, Stephen A DeLurgio, Mark A Clements

Open access · greenAbstract readValidation Study
In one paragraph

Article in Diabetes technology & therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Susana R Patton1 Division of Behavorial Pediatrics, Department of Pediatrics, University of Kansas Medical Center , Kansas City, Kansas.
Stephen A DeLurgio2 Children's Mercy Hospital , Kansas City, Missouri.
Mark A Clements3 Division of Endocrinology, Children's Mercy Hospital , Kansas City, Missouri.
Children's Mercy Hospital · USUniversity of Kansas Medical Center · US

Funding

Longitudinal test of adherence & control in kids new to T1 diabetes & 5-9 yrs oldR01DK100779 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NELSON, EVE-LYNN · 2014 to 2018
$1.8M
NIDDK NIH HHS R01-DK100779
6 · The paper itself

Abstract

objectiveThe Average Daily Risk Range (ADRR) is a measure of glycemic variability (GV) developed for adults with diabetes. Although the ADRR is increasingly being reported in pediatric diabetes research and may also be used in clinical management, it has never been examined for its sensitivity to predicting hyper- and hypoglycemia in youths or compared for its predictive ability with other measures of GV in youths. Thus, we present predictive validity data for the ADRR in youths with type 1 diabetes. MATERIALS AND

methodsGlucometer data for 436 youths (mean age, 11.8±3.8 years) were collected from a clinical database. Using these data, we computed the ADRR, SD of blood glucose, coefficient of variation of blood glucose, Low Blood Glucose Index, High Blood Glucose Index, the percentage of glucose values ≥70 and ≤180 mg/dL, the percentage of high glucose values >180 mg/dL and >400 mg/dL, and the percentage of low glucose values <70 mg/dL and <40 mg/dL in Month 1. We then compared these with episodes of hypo- and hyperglycemia in Month 2.

resultsThe ADRR showed good concurrent validity with other measures of GV in youths experiencing hyperglycemic events but limited predictive validity in general and specifically with future hypoglycemic events. The percentages of current hyper- and hypoglycemic episodes appeared to be stronger predictors of future hyper- and hypoglycemic episodes, respectively.

conclusionsIn a large pediatric sample, the ADRR was not the strongest predictor of future glycemic excursion. The percentages of current hyper- and hypoglycemic episodes appear to be stronger predictors.

Indexed as

AdolescentBlood GlucoseBlood Glucose Self-MonitoringChildDiabetes Mellitus, Type 1FemaleHumansHyperglycemiaHypoglycemiaMalePredictive Value of TestsReference ValuesReproducibility of ResultsSensitivity and SpecificityBlood Glucose

Identifiers

PMID26535929
PMCPMC4808279
OpenAlexW2210185912

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.