Evidence map›Paper›PMID 26568906›Full record

ArticleCurrent tropical medicine reports2015

Treatment of Cryptosporidium: What We Know, Gaps, and the Way Forward.

Hayley Sparks, Gayatri Nair, Alejandro Castellanos-Gonzalez, A Clinton White

Open access · hybridAbstract read
In one paragraph

Article in Current tropical medicine reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it, 138 citations in OpenAlex.

  1. Pathogens and global health · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Efficacy of nitazoxanide, ivermectin and albendazole in treatment of cryptosporidiosis in immunosuppressed mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Eugenol: effective complementary treatment for cryptosporidiosis in experimentally infected mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  11. Article
  12. Review
  13. Frontiers in veterinary science · 2024
    Article
  14. Article
  15. Article
  16. The First Identification ofVeterinary sciences · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Pharmaceuticals (Basel, Switzerland) · 2023
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hayley SparksInfectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch Galveston, 301 University Boulevard, Route 0435, Galveston, TX 77555-0435 USA, TeL 1-409-747-0236, FAX 1-409-772-6527.
Gayatri NairInfectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch Galveston, 301 University Boulevard, Route 0435, Galveston, TX 77555-0435 USA, TeL 1-409-747-0236, FAX 1-409-772-6527.
Alejandro Castellanos-GonzalezInfectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch Galveston, 301 University Boulevard, Route 0435, Galveston, TX 77555-0435 USA, TeL 1-409-747-0236, FAX 1-409-772-6527.
A Clinton WhiteInfectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch Galveston, 301 University Boulevard, Route 0435, Galveston, TX 77555-0435 USA, TeL 1-409-747-0236, FAX 1-409-772-6527.
The University of Texas Medical Branch at Galveston · US

Funding

Calcium Dependent Protein Kinase 1 as a drug target for T. gondii and C. parvumR01AI089441 · NIAID · UNIVERSITY OF WASHINGTON · PI MERRITT, ETHAN A, PARSONS, MARILYN · 2010 to 2014
$5.0M
NIAID NIH HHS R01 AI089441
6 · The paper itself

Abstract

Cryptosporidiosis is increasingly recognized as an important global health concern. While initially reported in immunocompromised such as AIDS patients, cryptosporidiosis has now been documented as a major cause of childhood diarrhea and an important factor in childhood malnutrition. Currently, nitazoxanide is the only proven anti-parasitic treatment for

Indexed as

cryptosporidiosisCryptosporidiumCryptosporidium hominisCryptosporidium parvumnitazoxanideparomomycin

Identifiers

PMID26568906
PMCPMC4640180
OpenAlexW991560763

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.