Evidence map›Paper›PMID 26576102›Full record

ReviewWorld journal of gastroenterology2015

Autoimmune gastritis: Pathologist's viewpoint.

Irene Coati, Matteo Fassan, Fabio Farinati, David Y Graham, Robert M Genta, Massimo Rugge

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Gastritis: Pathophysiology, Diagnosis, and Clinical Implications.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  7. Immunological mechanisms of autoimmune gastritis.Clinical and experimental medicine · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Gyrus-like endoscopic changes in autoimmune gastritis with pastWorld journal of gastrointestinal endoscopy · 2025
    Article
  14. Article
  15. Article
  16. Gastric cancer in patients withWorld journal of gastrointestinal oncology · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Irene CoatiIrene Coati, Matteo Fassan, Massimo Rugge, Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.
Matteo FassanIrene Coati, Matteo Fassan, Massimo Rugge, Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.
Fabio FarinatiIrene Coati, Matteo Fassan, Massimo Rugge, Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.
David Y GrahamIrene Coati, Matteo Fassan, Massimo Rugge, Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.
Robert M GentaIrene Coati, Matteo Fassan, Massimo Rugge, Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.
Massimo RuggeIrene Coati, Matteo Fassan, Massimo Rugge, Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, 35121 Padua, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Western countries are seeing a constant decline in the incidence of Helicobacter pylori-associated gastritis, coupled with a rising epidemiological and clinical impact of autoimmune gastritis. This latter gastropathy is due to autoimmune aggression targeting parietal cells through a complex interaction of auto-antibodies against the parietal cell proton pump and intrinsic factor, and sensitized T cells. Given the specific target of this aggression, autoimmune gastritis is typically restricted to the gastric corpus-fundus mucosa. In advanced cases, the oxyntic epithelia are replaced by atrophic (and metaplastic) mucosa, creating the phenotypic background in which both gastric neuroendocrine tumors and (intestinal-type) adenocarcinomas may develop. Despite improvements in our understanding of the phenotypic changes or cascades occurring in this autoimmune setting, no reliable biomarkers are available for identifying patients at higher risk of developing a gastric neoplasm. The standardization of autoimmune gastritis histology reports and classifications in diagnostic practice is a prerequisite for implementing definitive secondary prevention strategies based on multidisciplinary diagnostic approaches integrating endoscopy, serology, histology and molecular profiling.

Indexed as

Autoimmune DiseasesAutoimmunityBiomarkersBiopsyGastritisHumansImmunohistochemistryPathologyPredictive Value of TestsPrognosisStem CellsStomachBiomarkersAutoimmune gastritisCarcinoidsMetaplasiaOperative link for gastritis assessment staging

Identifiers

PMID26576102
PMCPMC4641135
OpenAlexW2396095149

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.