Evidence map›Paper›PMID 26601670›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Assessment of late anthracycline-induced cardiotoxicity by

Marcelo José Dos Santos, Euclides Timóteo da Rocha, Hein J Verberne, Eduardo Tinois da Silva, Davi Casale Aragon, José Soares Junior

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. MIBG cardiac imaging compared to ejection fraction in evaluation of cardiotoxicity: a systematic review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Pooled it
  3. Review
  4. Review
  5. Review
  6. CardiacPharmaceuticals (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Article
  9. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  10. Anthracycline-induced cardiotoxicity: Is there a role for myocardialJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  11. Article
  12. Precision Cardio-Oncology.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Review
  13. Review
  14. Anthracycline-induced cardiomyopathy: The search continues.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marcelo José Dos SantosDepartment of Nuclear Medicine, Pio XII Foundation, Barretos Cancer Hospital, Barretos, São Paulo, Zip code: 14.784-700, Brazil. marcelojosebr@yahoo.com.br.
Euclides Timóteo da RochaDepartment of Nuclear Medicine, Pio XII Foundation, Barretos Cancer Hospital, Barretos, São Paulo, Zip code: 14.784-700, Brazil.
Hein J VerberneDepartment of Nuclear Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Eduardo Tinois da SilvaISTRAD - Institute of Security and Technology on Radiation, Campinas, São Paulo, Brazil.
Davi Casale AragonDepartment of Pediatrics, Medical School of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
José Soares JuniorThe Heart Institute (Incor), Medical School of São Paulo, University of São Paulo, São Paulo, Brazil.
Hospital de Câncer de Barretos · BRUniversidade de São Paulo · BRUniversity of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goal of this study was to evaluate late cardiotoxic effects of anthracyclines (ATC) by evaluating cardiac sympathetic activity in a cohort of asymptomatic patients previously treated with ATC for childhood cancers.

methodsWe studied 89 asymptomatic patients previously treated with ATC with a normal echocardiogram (49 men and 40 women) and a control group of 40 healthy individuals (26 men and 14 women). Both groups underwent planar myocardial

resultsThe mean survival at the time of the

conclusionsAlthough the pathophysiology behind ATC cardiotoxicity is most likely multifactorial, myocardial sympathetic activity is not associated with a reduction in LVEF 5-years after completion of chemotherapy.

Indexed as

3-IodobenzylguanidineAdolescentAdultAnthracyclinesAntineoplastic AgentsAutonomic Nervous System DiseasesBrazilCardiotoxicityCausalityChildChild, PreschoolComorbidityFemaleHumansMaleNeoplasms3-IodobenzylguanidineAnthracyclinesAntineoplastic AgentsRadiopharmaceuticals123I-mIBGanthracyclineCardiac sympathetic activityleft ventricular function

Identifiers

PMID26601670
OpenAlexW2301701086

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.