Evidence map›Paper›PMID 26657706›Full record

ArticleAmerican journal of hypertension2016

Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study.

Ricky Camplain, Michelle L Meyer, Hirofumi Tanaka, Priya Palta, Sunil K Agarwal, David Aguilar, Kenneth R Butler, Gerardo Heiss

Open access · bronzeAbstract read
In one paragraph

Article in American journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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  16. Association of cigarette smoking with radial augmentation index: the Circulatory Risk in Communities Study (CIRCS).Hypertension research : official journal of the Japanese Society of Hypertension · 2018
    Article
  17. Parameters of pulse wave velocity: determinants and reference values assessed in the population-based study LIFE-Adult.Clinical research in cardiology : official journal of the German Cardiac Society · 2018
    Article
  18. Histone 3 modifications and blood pressure in the Beijing Truck Driver Air Pollution Study.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2017
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Ricky CamplainUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; camplain@email.unc.edu.
Michelle L MeyerUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
Hirofumi TanakaUniversity of Texas at Austin, Austin, Texas, USA;
Priya PaltaUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
Sunil K AgarwalJohns Hopkins University, Baltimore, Maryland, USA;
David AguilarBaylor College of Medicine, Houston, Texas, USA;
Kenneth R ButlerUniversity of Mississippi Medical Center, Jackson, Mississippi, USA.
Gerardo HeissUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
University of North Carolina at Chapel Hill · USBaylor College of Medicine · USJackson Memorial Hospital · USJohns Hopkins University · USThe University of Texas at Austin · US

Funding

Atherosclerosis, Plaque and CVD in CommunitiesU01HL075572 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BOERWINKLE, ERIC A · 2004 to 2007
$15.6M
Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS T32 HL007055NHLBI NIH HHS U01 HL075572
6 · The paper itself

Abstract

backgroundThough smoking is strongly associated with peripheral vascular disease and arteriosclerosis, smoking's association with arterial stiffness has been inconsistent and mostly limited to a single arterial segment. We examined the relationship between smoking behaviors with arterial stiffness in multiple arterial segments among community dwelling older adults.

methodsThe cross-sectional relationship between smoking behavior with carotid-femoral (cfPWV) and femoral-ankle pulse wave velocity (faPWV) was examined in 5,002 men and women, separately, of the Atherosclerosis Risk in Communities (ARIC) cohort study. Brachial-ankle PWV was also assessed and presented in Supplementary Material. Heckman selection models were used to control for selective attrition and death in the ARIC cohort.

resultsIn women, faPWV was lower in current smokers compared to never smokers (-66.0cm/s; 95% confidence interval (95% CI): -94.6, -37.4), and was 1.0cm/s lower (95% CI: -1.8, -0.2) for every additional year a woman smoked, after adjustment for confounders. Among women, cfPWV was not associated with smoking status or cigarette pack-years. Additionally, no associations of smoking status and cigarette pack-years with PWV were observed among men. Years since smoking cessation was not associated with PWV in either gender.

conclusionBoth smoking status and cumulative smoking exposure were associated with lower peripheral arterial stiffness among women, but not among men. We did not observe an association between central arterial stiffness and smoking status in either gender. The profound and well-documented adverse effects of cigarette smoking on the vasculature may not include a sustained stiffening of the arteries measured at older age.

Indexed as

arterial stiffnessarteriosclerosisblood pressurecentral and peripheral arterial stiffnesshealth behaviorhypertensionsmokingsmoking cessationsubclinical cardiovascular disease.

Identifiers

PMID26657706
PMCPMC5055735
OpenAlexW2280834742

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.