Evidence map›Paper›PMID 26664101›Full record

Trial reportClinical interventions in aging2015

Effect of Nordic Walking training on iron metabolism in elderly women.

Jakub Kortas, Katarzyna Prusik, Damian Flis, Krzysztof Prusik, Ewa Ziemann, Neil Leaver, Jedrzej Antosiewicz

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Clinical interventions in aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

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  5. Simple sugar supplementation abrogates exercise-induced increase in hepcidin in young men.Journal of the International Society of Sports Nutrition · 2017
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  10. Impact of resistance training and basic ferritin on hepcidin, iron status and some inflammatory markers in overweight/obese girls.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
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  14. Marathon Run-induced Changes in the Erythropoietin-Erythroferrone-Hepcidin Axis are Iron Dependent.International journal of environmental research and public health · 2020
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  16. Effect ofClinical interventions in aging · 2020
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jakub KortasDepartment of Recreation and Tourism, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Katarzyna PrusikDepartment of Biomedical Basis of Health, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Damian FlisDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, Gdansk, Poland.
Krzysztof PrusikDepartment of Recreation and Tourism, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Ewa ZiemannDepartment of Physiology and Pharmacology, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Neil LeaverThe Immunosuppression monitoring service (IMS) Laboratory, Royal Brompton & Harefield NHS Foundation Trust, Heart Science Centre, Harefield Hospital, Harefield, UK.
Jedrzej AntosiewiczDepartment of Biochemistry, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Gdansk University of Physical Education and Sport · PLGdańsk Medical University · PLHarefield Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite several, well-documented pro-healthy effects of regular physical training, its influence on body iron stores in elderly people remains unknown. At the same time, body iron accumulation is associated with high risk of different morbidities. PURPOSE: We hypothesized that Nordic Walking training would result in pro-healthy changes in an elderly group of subjects by reducing body iron stores via shifts in iron metabolism-regulating proteins.

methodsThirty-seven women aged 67.7±5.3 years participated in this study. They underwent 32 weeks of training, 1-hour sessions three times a week, between October 2012 and May 2013. Fitness level, blood morphology, CRP, vitamin D, ferritin, hepcidin, and soluble Hjv were assessed before and after the training.

resultsThe training program caused a significant decrease in ferritin, which serves as a good marker of body iron stores. Simultaneously, the physical cardiorespiratory fitness had improved. Furthermore, blood hepcidin was positively correlated with the ferritin concentration after the training. The concentration of blood CRP dropped, but the change was nonsignificant. The applied training resulted in a blood Hjv increase, which was inversely correlated with the vitamin D concentration.

conclusionOverall the Nordic Walking training applied in elderly people significantly reduced blood ferritin concentration, which explains the observed decrease in body iron stores.

Indexed as

AgedBody Weights and MeasuresC-Reactive ProteinExerciseFemaleFerritinsHematologic TestsHepcidinsHumansIronPhysical FitnessVitamin DWalkingC-Reactive ProteinFerritinsHepcidinsIronVitamin Danti-agingferritinhemojuvelinhepcidinvitamin D

Identifiers

PMID26664101
PMCPMC4669095
OpenAlexW2172359079

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.