Trial reportContemporary clinical trials2016
A clinical trial to examine disparities in quitting between African-American and White adult smokers: Design, accrual, and baseline characteristics.
Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01836276 (Understanding Disparities in Quitting in African American and White Smokers), which is not on this map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Understanding Disparities in Quitting in African American and White Smokers
Who cites it
15 citing papers in PubMed.
- The effect of area-level disadvantage and race on smoking abstinence in a clinical trial.Experimental and clinical psychopharmacology · 2022Trial
- Impact of early nausea on varenicline adherence and smoking cessation.Addiction (Abingdon, England) · 2020Trial
- Prediction and monitoring of accrual and rate of underrepresented biomedical research group using bayesian methods.BMC medical research methodology · 2026Article
- Features of Mobile Health Apps for Tobacco Cessation That Appeal to Black Adults Who Use Tobacco Products: Focus Group Study.JMIR mHealth and uHealth · 2026Article
- Religiosity vs tobacco use: Religion's impact on tobacco use among adult Indian population - A cross sectional study.Journal of family medicine and primary care · 2024Article
- Genotyping, characterization, and imputation of known and novel CYP2A6 structural variants using SNP array data.Journal of human genetics · 2023Article
- Protocol from a randomized clinical trial of multiple pharmacotherapy adaptations based on treatment response in African Americans who smoke.Contemporary clinical trials communications · 2022Article
- The Role of Financial Strain and Educational Attainment on Smoking Abstinence of African Americans and Whites Who Smoke.Ethnicity & disease · 2022Article
- The Role of Neighborhood Experiences in Psychological Distress among African American and White Smokers.Race and social problems · 2020Article
- Comparison of a Collective Intelligence Tailored Messaging System on Smoking Cessation Between African American and White People Who Smoke: Quasi-Experimental Design.JMIR mHealth and uHealth · 2020Article
- Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity.Addiction biology · 2020Article
- Darker skin color is associated with a lower likelihood of smoking cessation among males but not females.Social science & medicine (1982) · 2019Article
- Factors That Explain Differences in Abstinence Between Black and White Smokers: A Prospective Intervention Study.Journal of the National Cancer Institute · 2019Article
- A randomized clinical trial of counseling and nicotine replacement therapy for treatment of African American non-daily smokers: Design, accrual, and baseline characteristics.Contemporary clinical trials · 2018Article
- Tobacco toxicant exposure in cigarette smokers who use or do not use other tobacco products.Drug and alcohol dependence · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundAfrican-Americans smoke fewer cigarettes per day than Whites but experience greater smoking attributable morbidity and mortality. African-American-White differences may also exist in cessation but rigorously designed studies have not been conducted to empirically answer this question. METHODS/
designQuit2Live is, to our knowledge, the first head-to-head trial designed with the primary aim of examining African-American-White disparities in quitting smoking. Secondary aims are to identify mechanisms that mediate and/or moderate the relationship between race and quitting. The study is ongoing. Study aims are accomplished through a 5-year prospective cohort intervention study designed to recruit equal numbers of African-Americans (n=224) and Whites (n=224) stratified on age (<40, ≥40) and gender, key factors known to impact cessation, and all within a restricted income range (≤400% federal poverty level). All participants will receive 12 weeks of varenicline in combination with smoking cessation counseling. The primary outcome is cotinine-verified 7-day point prevalence abstinence from smoking at week 26. Secondary outcomes are cotinine-verified 7-day point prevalence abstinence from smoking at weeks 4 and 12. DISCUSSION: Findings from Quit2Live will not only address if African-American-White disparities in quitting smoking exist but, more importantly, will examine mechanisms underlying the difference. Attention to proximal, modifiable mechanisms (e.g., adherence, response to treatment, depression, stress) maximizes Quit2Live's potential to inform practice. Findings will provide an empirically-derived approach that will guide researchers and clinicians in identifying specific factors to address to improve cessation outcomes and reduce tobacco-related morbidity and mortality in African-American and White smokers. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov: NCT01836276.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.