ReviewBBA clinical2015
Cardiometabolic and vascular risks in young and adolescent girls with Turner syndrome.
Review in BBA clinical, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Endothelial Peripheral Arterial Tonometry (Endo-PAT 2000) use in paediatric patients: a systematic review.BMJ open · 2023Pooled it
- Metabolic features and postoperative outcomes in Turner syndrome with congenital heart disease.Pediatric research · 2026Article
- An Overview of Oxidative Stress in Sex Chromosome Aneuploidies in Pediatric Populations.Antioxidants (Basel, Switzerland) · 2025Review
- Carotid Intima-Media Thickness and Cardiometabolic Profile in Turner Syndrome: A Cross-Sectional Study.Cureus · 2024Article
- Outcomes of cardiothoracic surgery in women with Turner syndrome.Annals of cardiothoracic surgery · 2023Article
- A rare case of mixed gonadal dysgenesis in adulthood: diagnostic delay and unique outcomes.Journal of surgical case reports · 2023Article
- Metabolic consequences of recombinant human growth hormone therapy in patients with Turner syndrome.Pediatric endocrinology, diabetes, and metabolism · 2023Article
- Liver Abnormalities in Turner Syndrome: The Importance of Estrogen Replacement.Journal of the Endocrine Society · 2022Review
- MicroRNA-126-3p/5p and Aortic Stiffness in Patients with Turner Syndrome.Children (Basel, Switzerland) · 2022Article
- Left atrial remodelling among Turner syndrome patients: novel insights from non-invasive 3D echocardiography.Quantitative imaging in medicine and surgery · 2022Article
- Cardiovascular Care of Turner Syndrome Women in Germany: Where Do We Stand?-Results from an Online Patient Survey.Healthcare (Basel, Switzerland) · 2022Article
- DNA Methylation Analysis of Turner Syndrome BAV.Frontiers in genetics · 2022Article
- Physical Activity and Diet Quality: Effects on Cardiovascular Morbidity in Women with Turner Syndrome-Results from an Online Patient Survey.Journal of clinical medicine · 2021Article
- Health behaviour of women with Turner Syndrome.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
- Body composition, but not insulin resistance, influences postprandial lipemia in patients with Turner's syndrome.Archives of endocrinology and metabolism · 2021Article
- Left ventricular remodelling among Turner syndrome patients: insights from non-invasive 3D echocardiography-derived pressure-volume loop analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2020Article
- Levonorgestrel correlates with less weight gain than other progestins during hormonal replacement therapy in Turner Syndrome patients.Scientific reports · 2020Article
- Metabolic Fingerprint of Turner Syndrome.Journal of clinical medicine · 2020Article
- A mixed methods study of physical activity and quality of life in adolescents with Turner syndrome.American journal of medical genetics. Part A · 2020Article
- Insights from circulating microRNAs in cardiovascular entities in turner syndrome patients.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTurner syndrome (TS) is the most common chromosomal abnormality in females and is associated with several co-morbidities. It commonly results from X monosomy which is diagnosed on a 30 cell karyotype. Congenital heart disease is a clinical feature in 30% of cases. It is becoming evident that TS patients have an increased risk of cardiovascular and cerebrovascular diseases. SCOPE OF REVIEW: This review provides a detailed overview of the literature surrounding cardiometabolic health in childhood and adolescent TS. In addition, the review also summarises the current data on the impact of growth hormone (GH) therapy on cardiometabolic risk in paediatric TS patients. MAJOR
conclusionsCurrent epidemiological evidence suggests that young women and girls with TS have unfavourable cardiometabolic risk factors which predispose them to adverse cardiac and cerebrovascular outcomes in young adulthood. It remains unclear whether this risk is the result of unidentified factors which are intrinsic to TS, or whether modifiable risk factors (obesity, hypertension, hyperglycaemia) are contributing to this risk. GENERAL SIGNIFICANCE: From a clinical perspective, this review highlights the importance of regular screening and pro-active management of cardiometabolic risk from childhood in TS cohorts and that future research should aim to address whether modification of these variables at a young age can alter the disease process and atherosclerotic outcomes in adulthood.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.