Evidence map›Paper›PMID 26712605›Full record

Trial reportEuropean journal of applied physiology2016

Exercise at lunchtime: effect on glycemic control and oxidative stress in middle-aged men with type 2 diabetes.

Jonida Haxhi, Gaetano Leto, Alessandro Scotto di Palumbo, Paola Sbriccoli, Laura Guidetti, Cristina Fantini, Raffaella Buzzetti, Daniela Caporossi, Luigi Di Luigi, Massimo Sacchetti

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 9 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 9 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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  11. Twenty Minute Moderate-Intensity Post-Dinner Exercise Reduces the Postprandial Glucose Response in Chinese Patients with Type 2 Diabetes.Medical science monitor : international medical journal of experimental and clinical research · 2018
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jonida HaxhiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Gaetano LetoDepartment of Experimental Medicine, Sapienza University of Rome, Polo Pontino, Viale del Policlinico 155, Rome, Italy.
Alessandro Scotto di PalumboDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Paola SbriccoliDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Laura GuidettiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Cristina FantiniDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Raffaella BuzzettiDepartment of Experimental Medicine, Sapienza University of Rome, Polo Pontino, Viale del Policlinico 155, Rome, Italy.
Daniela CaporossiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Luigi Di LuigiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy.
Massimo SacchettiDepartment of Movement, Human and Health Sciences, University of Rome Foro Italico, Piazza Lauro de Bosis 6, Rome, Italy. massimo.sacchetti@uniroma4.it.
Foro Italico University of Rome · ITPoliclinico Umberto I · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostprandial hyperglycemia and glycemic oscillations have been associated with increased oxidative stress. We sought to investigate the effect of two walking exercise protocols performed during lunchtime on glycemic control and oxidative stress in type 2 diabetic (T2D) patients.

methodsNine T2D patients participated in three randomized crossover trials; a control trial (Con), with participants having a standard lunch followed by their normal daily activities and two exercise trials (ContEx and Splitex). In ContEx, subjects performed 40 min of brisk walking 40 min after lunch, whereas in SplitEx the walking exercise was divided in two 20-min isoenergetic bouts, before and 40 min after meal. 24-h glycemic control was monitored by continuous glucose monitoring. 24-h urinary levels of 8-iso PGF2ɑ were measured as a marker of oxidative stress.

resultsSplitEx resulted in less time spent in moderate hyperglycemia after lunch vs ContEx (42.4 ± 38.7% vs 68.2 ± 32.7%, P = 0.04). ContEx reduced hyperglycemic time after breakfast consumed the morning after the exercise session (58.3 ± 29.6 Con vs 40.2 ± 33.4% ContEx, P = 0.02). Compared with Con, 24-h urinary isoprostanes were decreased both in ContEx (-68%, P = 0.02) and SplitEx (-63%, P = 0.04).

conclusionsSplitting an exercise session into two bouts, pre- and post-lunch, affects mainly the glycemic response to lunch, while a single-continuous isoenergetic session exerts its effect later in the 24-h period. Both exercise modalities effectively attenuate systemic oxidative stress with similar overall benefits.

Indexed as

Exercise TherapyOxidative StressWalkingAgedBlood GlucoseDiabetes Mellitus, Type 2HumansLunchMaleMiddle AgedPostprandial PeriodBlood GlucoseBrisk walkingContinuous glucose monitoringExercise timingPostprandial hyperglycemiaUrinary isoprostanes

Identifiers

PMID26712605
OpenAlexW2199990455

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.