Evidence map›Paper›PMID 26715392›Full record

ArticleCell biology and toxicology2015

Structural and functional changes in the zebrafish (Danio rerio) skeletal muscle after cadmium exposure.

Bice Avallone, Claudio Agnisola, Raimondo Cerciello, Raffaele Panzuto, Palma Simoniello, Patrizia Cretì, Chiara Maria Motta

Abstract read
In one paragraph

Article in Cell biology and toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle.Journal of toxicology and environmental health. Part B, Critical reviews · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Effects of Cadmium Exposure on Gut Villi inInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Review
  13. Cadmium Accumulation and Depuration in the Muscle of Prussian Carp (Animals : an open access journal from MDPI · 2021
    Article
  14. Article
  15. Article
  16. The neurological toxicity of heavy metals: A fish perspective.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018
    Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bice AvalloneDepartment of Biology, University of Naples Federico II, Via Mezzocannone 8, Naples, 80134, Italy. bice.avallone@unina.it.ORCID http://orcid.org/0000-0002-5355-1557
Claudio AgnisolaDepartment of Biology, University of Naples Federico II, Via Mezzocannone 8, Naples, 80134, Italy.
Raimondo CercielloDepartment of Biology, University of Naples Federico II, Via Mezzocannone 8, Naples, 80134, Italy.
Raffaele PanzutoDepartment of Biology, University of Naples Federico II, Via Mezzocannone 8, Naples, 80134, Italy.
Palma SimonielloDepartment of Biophysics, GSI Helmholtz Center for Heavy Ion Research, Darmstadt, 64291, Germany.
Patrizia CretìDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Lecce, Italy.
Chiara Maria MottaDepartment of Biology, University of Naples Federico II, Via Mezzocannone 8, Naples, 80134, Italy.

Funding

Structural Biology Facility CoreP30ES000267 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 1985 to 2014
$20.3M
Mechanisms of Manganese NeurotoxicityR01ES010563 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 2001 to 2026
$11.9M
NIEHS NIH HHS P30 ES000267NIEHS NIH HHS R01 ES010563
6 · The paper itself

Abstract

This report describes the alterations induced by an environmentally realistic concentration of cadmium in skeletal muscle fibre organization, composition, and function in the teleost zebrafish. Results demonstrate that the ion induces a significant quantitative and qualitative deterioration, disrupting sarcomeric pattern and altering glycoprotein composition. These events, together with a mitochondrial damage, result in a significant reduction in swimming performance. In conclusion, the evidence here collected indicate that in presence of an environmental cadmium contamination, important economic (yields in fisheries/aquaculture), consumer health (fish is an important source of proteins), and ecological (reduced fitness due to reduced swimming performance) consequences can be expected.

Indexed as

AnimalsBehavior, AnimalCadmiumCations, DivalentFish ProteinsGlycoproteinsMaleMitochondriaMuscle Fibers, SkeletalSarcomeresSwimmingWater Pollutants, ChemicalZebrafishCadmiumCations, DivalentFish ProteinsGlycoproteinsWater Pollutants, ChemicalBehavioral testsCadmiumLectinsToxicityUcritUltrastructure

Identifiers

PMID26715392
PMCPMC6525712

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.