ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
The association between the prevalence, treatment and control of hypertension and the risk of mild cognitive impairment in an elderly urban population in China.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- The complex burden of determining prevalence rates of mild cognitive impairment: A systematic review.Frontiers in psychiatry · 2022Pooled it
- Screening for mild cognitive impairment in people with obesity: a systematic review.BMC endocrine disorders · 2021Pooled it
- Prevalence of mild cognitive impairment in community-dwelling Chinese populations aged over 55 years: a meta-analysis and systematic review.BMC geriatrics · 2021Pooled it
- Left ventricular hypertrophy in association with cognitive impairment: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Pooled it
- The Role and Therapeutic Potential of the cGAS-STING Signaling Pathway in Alzheimer's Disease.Brain and behavior · 2025Review
- Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers.Frontiers in nutrition · 2025Article
- Article
- Association between physical activity and falls among older adults in rural China: are there gender and age related differences?BMC public health · 2022Article
- Poor sleep quality is negatively associated with low cognitive performance in general population independent of self-reported sleep disordered breathing.BMC public health · 2022Article
- Gender-specific prevalence and risk factors of mild cognitive impairment among older adults in Chongming, Shanghai, China.Frontiers in aging neuroscience · 2022Article
- The Association Between the Prevalence, Medication Adherence and Control of Hypertension and the Prevalence of Mild Cognitive Impairment in Rural Northern China: A Cross-Sectional Study.Patient preference and adherence · 2022Article
- Association between 24-h urinary sodium to potassium ratio and mild cognitive impairment in community-based general population.Public health nutrition · 2021Article
- Burden and correlates of cognitive impairment among hypertensive patients in Tanzania: a cross-sectional study.BMC neurology · 2021Article
- Article
- Socioeconomic and lifestyle determinants of the prevalence of hypertension among elderly individuals in rural southwest China: a structural equation modelling approach.BMC cardiovascular disorders · 2021Article
- Body mass index and mild cognitive impairment among rural older adults in China: the moderating roles of gender and age.BMC psychiatry · 2021Article
- Synergistic Effects of Aldehyde Dehydrogenase 2 Polymorphisms and Alcohol Consumption on Cognitive Impairment after Ischemic Stroke in Han Chinese.Behavioural neurology · 2021Article
- Multicentric evidence of emotional impairments in hypertensive heart disease.Scientific reports · 2020Article
- Article
- Non-communicable Diseases and Cognitive Impairment: Pathways and Shared Behavioral Risk Factors Among Older Chinese.Frontiers in public health · 2019Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It remains unclear whether lowering the blood pressure effectively prevents cognitive impairment. The aim of the current study was to explore the association between the prevalence, treatment and control of hypertension and the risk of mild cognitive impairment (MCI) among elderly Chinese people. This is a cross-sectional study conducted in Beijing, China. A two-stage stratified clustering sampling method was used, and 2065 participants, aged ⩾60 years, were included in the analysis. The Mini-Mental State Examination was used to assess participants' cognitive function. The prevalence of MCI was higher in hypertensive (16.5%) than in normotensive individuals (13.1%; P=0.043). Furthermore, in those hypertensive patients, the prevalence of MCI was lower in those treated (14.9%) than in those not treated (19.9%; P=0.019) and lower in those controlled (13.4%) than in those uncontrolled (17.9%; P=0.042). The adjusted odds ratio (OR; 95% confidence interval (CI)) of having MCI was 1.59 (1.07-2.35) in those with hypertension compared with those normotensive individuals. The assessment of the hypertensive patients revealed the adjusted OR (95% CI) of having MCI in those with treated hypertension was 0.60 (0.42-0.86) compared with those untreated hypertension, and in those with controlled hypertension was 0.64 (0.43-0.93) compared with those non-controlled hypertension (regardless of treatment). However, among the treated hypertensive patients, there was no difference in the prevalence of MCI between the patients who reached and those who did not reach their treatment goal. We suggest that improved diagnoses and optimal therapeutics are needed to achieve the aim of cognitive decline prevention.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.