Evidence map›Paper›PMID 26805801›Full record

ArticleMolecules (Basel, Switzerland)2016

The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol.

Peter Kotora, František Šeršeň, Juraj Filo, Dušan Loos, Juraj Gregáň, Fridrich Gregáň

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  7. Exploring the chemical composition, medicinal benefits, and antioxidant activity ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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  15. Myeloperoxidase Inhibitory and Antioxidant Activities of (Pharmaceuticals (Basel, Switzerland) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peter KotoraInstitute of Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, 842 15 Bratislava, Slovakia. kotora@fns.uniba.sk.
František ŠeršeňInstitute of Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, 842 15 Bratislava, Slovakia. f.sersen@gmail.com.
Juraj FiloInstitute of Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, 842 15 Bratislava, Slovakia. filo@fns.uniba.sk.
Dušan LoosInstitute of Chemistry, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, 842 15 Bratislava, Slovakia. dusan.looos@chello.sk.
Juraj GregáňDepartment of Genetics, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, 842 15 Bratislava, Slovakia. juraj.gregan@univie.ac.at.
Fridrich GregáňDepartment of Chemistry, Faculty of Natural Sciences, Matej Bell University, Tajovského 40, 974 01 Banská Bystrica, Slovakia. Fridrich.Gregan@umb.sk.

Funding

Austrian Science Fund FWF P 21437Austrian Science Fund FWF P 23609
6 · The paper itself

Abstract

Resveratrol (3,5,4'-trihydroxystilbene) is a phytoalexin produced by plants. Resveratrol is known for its anti-cancer, antiviral and antioxidant properties. We prepared imine analogs of resveratrol ((hydroxyphenyliminomethyl)phenols) and tested their antioxidant activity. All prepared resveratrol analogs were able to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH), galvinoxyl radical (GOR) and 2,2'-azino-bis(3-ethylbenzothiazoline)-6-sulphonic acid (ABTS) radicals. The antioxidant activity efficiency correlated with the number and position of hydroxyl groups. The most effective antioxidants were resveratrol analogs containing three hydroxyl groups in the benzylidene part of their molecules. These results provide new insights into the relationship between the chemical structure and biological activity of resveratrol analogs.

Indexed as

Benzhydryl CompoundsBenzothiazolesBiphenyl CompoundsFree Radical ScavengersMolecular StructurePicratesResveratrolStilbenesSulfonic Acids1,1-diphenyl-2-picrylhydrazyl2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidBenzhydryl CompoundsBenzothiazolesBiphenyl CompoundsFree Radical ScavengersgalvinoxylPicratesResveratrolStilbenesSulfonic Acidsantioxidant activityiminophenolsresveratrol analogs

Identifiers

PMID26805801
PMCPMC4759939

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.