ArticleQuantitative imaging in medicine and surgery2015
Impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine indexes of cardiac sympathetic innervation.
Article in Quantitative imaging in medicine and surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Review
- Imaging techniques for the assessment of adverse cardiac remodeling in metabolic syndrome.Heart failure reviews · 2022Review
- Dosing Therapeutic Radiopharmaceuticals in Obese Patients.International journal of molecular sciences · 2022Review
- Abdominal obesity, and not general obesity, is associated with a lower 123I MIBG heart-to-mediastinum ratio in heart failure patients with preserved ejection fraction.European journal of nuclear medicine and molecular imaging · 2022Article
- CardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Diabesity: the combined burden of obesity and diabetes on heart disease and the role of imaging.Nature reviews. Cardiology · 2021Review
- Cardiovascular Imaging in Obesity.Nutrients · 2021Review
- Impact of body mass index on cardiac adrenergic derangement in heart failure patients: aEuropean journal of nuclear medicine and molecular imaging · 2020Article
- CMR stress testing in a patient with morbid obesity (BMI 58 kg/mBMC cardiovascular disorders · 2018Article
- Challenges and opportunities of noninvasive cardiac imaging in obesity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Myocardial perfusion scintigraphy dosimetry: optimal use of SPECT and SPECT/CT technologies in stress-first imaging protocol.Clinical and translational imaging · 2016Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was designed to assess the impact of obesity and acquisition protocol on (123)I-metaiodobenzylguanidine (MIBG) indexes of cardiac sympathetic innervation.
methodsForty-five patients with heart failure (HF) (38 men, age 58±15 years) underwent (123)I-MIBG cardiac imaging. Of these patients, 10 were obese [body mass index (BMI) ≥30 kg/m(2)]. Ten-minute planar images of the thorax in anterior view were performed 15 minutes ("early" image) and 3 hours and 50 minutes ("late" image) after tracer administration in both supine- and prone-position. Early and late (123)I-MIBG heart-to-mediastinum (H/M) ratios and washout rate were computed.
resultsIn overall study population, early and late (123)I-MIBG H/M ratios and washout rate were comparable between supine- and prone-position acquisitions. Obese patients had a lower early and late (123)I-MIBG H/M ratios both in supine (P<0.01) and prone (P<0.05) positions compared to non-obese subjects.
conclusionsOur results indicate that in HF patients, obesity has a significant impact on (123)I-MIBG indexes of cardiac sympathetic innervation. Prone-position did not change early and late (123)I-MIBG H/M ratios and washout rate compared to supine position both in obese and non-obese HF patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.