ReviewWorld journal of gastroenterology2016
Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance.
Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Prevalence of Gastric Precursor Lesions in Countries With Differential Gastric Cancer Burden: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024Pooled it
- Impact of Rifaximin, a Gut-Selective Antibiotic, on Gastric Intestinal Metaplasia: A Retrospective Study.Journal of clinical medicine · 2026Article
- The prevalence of gastric intestinal metaplasia in the Saudi population: a single-tertiary center retrospective study.Journal of gastrointestinal oncology · 2026Article
- Autoimmune Gastritis and Gastric Cancer Risk: Endoscopic and Histopathological Outcomes.Journal of clinical medicine · 2026Article
- Taurine suppresses gastric intestinal metaplasia in patient-derived organoids andWorld journal of gastrointestinal oncology · 2026Article
- Endoscopic and histopathological phenotypes of early gastric neoplasia: toward an integrative host-response framework.Frontiers in oncology · 2026Review
- Hsp60-Bearing Exosomes inCells · 2025Review
- Galangin alleviates gastric mucosal injury in rats with chronic atrophic gastritis by reducing ferroptosis.Histology and histopathology · 2025Article
- The Potential Role of the Rapid Urease Test with the Sweeping Method in the Gray Zone of the Urea Breath Test afterGut and liver · 2025Article
- Long-term Clinical Efficacy of Radiotherapy for Patients with Stage I-II Gastric Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue: A Retrospective Multi-institutional Study.Cancer research and treatment · 2025Article
- Influence ofHeliyon · 2024Article
- Global burden and risk factors of gastritis and duodenitis: an observational trend study from 1990 to 2019.Scientific reports · 2024Observational
- Article
- Eradication efficacy of high-dose amoxicillin and proton pump inhibitor compared with quadruple therapy contained bismuth in the treatment ofJournal of family medicine and primary care · 2022Article
- Roles and action mechanisms of bile acid-induced gastric intestinal metaplasia: a review.Cell death discovery · 2022Review
- Article
- Essential role of ALKBH5-mediated RNA demethylation modification in bile acid-induced gastric intestinal metaplasia.Molecular therapy. Nucleic acids · 2021Article
- Association of specific haplotype of tumor necrosis factor-α and interleukin-1β polymorphisms withGerms · 2021Article
- The role of the occupational physician in controlling gastric cancer attributable toPreventive medicine reports · 2021Review
- Plasmacytoid Dendritic Cell-Derived Type I Interferon Is Involved in Helicobacter pylori Infection-Induced Differentiation of Schlafen 4-Expressing Myeloid-Derived Suppressor Cells.Infection and immunity · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric cancer (GC) is one of the leading causes of cancer related death in the world, particularly in East Asia. According to the Correa's cancer cascade, non-cardia GC is usually developed through a series of mucosal changes from non-atrophic gastritis to atrophic gastritis (AG), intestinal metaplasia (IM), dysplasia and adenocarcinoma. Atrophic gastritis and IM are therefore generally considered to be pre-neoplastic gastric lesions. Helicobacter pylori (H. pylori) infection is an important initiating and promoting step of this gastric carcinogenesis cascade. Emerging long-term data showed that eradication of H. pylori reduced the risk of subsequent cancer development. It however remains confusing whether eradication of the bacterium in individuals with pre-neoplastic gastric lesions could regress these changes as well as in preventing cancer. Whilst H. pylori eradication could likely regress AG, the presence of IM may be a point of no return in this cascade. Hence, surveillance by endoscopy may be indicated in those with extensive IM or those with incomplete IM, particularly in populations with high GC risk. The optimal interval and the best tool of surveillance endoscopy remains to be determined in future studies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.