Evidence map›Paper›PMID 26819522›Full record

ReviewWorld journal of gastroenterology2016

Post reperfusion syndrome during liver transplantation: From pathophysiology to therapy and preventive strategies.

Antonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Giorgio Ercolani, Laura Lorenzini, Stefano Faenza

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antonio SiniscalchiAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Lorenzo GamberiniAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Cristiana LaiciAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Tommaso BardiAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Giorgio ErcolaniAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Laura LorenziniAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.
Stefano FaenzaAntonio Siniscalchi, Lorenzo Gamberini, Cristiana Laici, Tommaso Bardi, Laura Lorenzini, Stefano Faenza, Division of Anesthesiology, Alma Mater Studiorum University of Bologna, 40138 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aims at evaluating the existing evidence regarding post reperfusion syndrome, providing a description of the pathophysiologic mechanisms involved and possible management and preventive strategies. A PubMed search was conducted using the MeSH database, "Reperfusion" AND "liver transplantation" were the combined MeSH headings; EMBASE and the Cochrane library were also searched using the same terms. 52 relevant studies and one ongoing trial were found. The concept of post reperfusion syndrome has evolved through years to a multisystemic disorder. The implications of the main organ, recipient and procedure related factors in the genesis of this complex syndrome are discussed in the text as the novel pharmacologic and technical approaches to reduce its incidence. However the available evidence about risk factors, physiopathology and preventive measures is still confusing, the presence of two main definitions and the numerosity of possible confounding factors greatly complicates the interpretation of the studies.

Indexed as

HemodynamicsLiver CirculationAnimalsHumansLiver TransplantationModels, AnimalReperfusion InjuryRisk FactorsTreatment OutcomeDrug therapyHemodynamicsIschemia-reperfusion injuryLiver transplantationReperfusion

Identifiers

PMID26819522
PMCPMC4721988

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.