Evidence map›Paper›PMID 26835847›Full record

ReviewAgeing research reviews2016

Hypertension and aging.

Thomas W Buford

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Ageing research reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 283 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
283citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03046420 completednot on this mapstarted 2017, after this paper: background citation

Hypertension Prevalence, Treatment Patterns and Outcomes in Long-Term Care Facilities

TypeobservationalSponsorLouisiana State University Health Sciences Center in New OrleansRan2017 to 2018Enrolled139ConditionsHypertensionArmsChart review
NCT03579108 unknown statusnot on this mapstarted 2018, after this paper: background citation

Hypertension Management and Outcomes in a Family Practice Setting

TypeobservationalSponsorLouisiana State University Health Sciences Center in New OrleansRan2018 to 2024Enrolled200ConditionsHypertensionArmsRetrospective Chart Review
3 · Its place in the literature

Who cites it

283 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  6. Hypertension and Alzheimer's disease pathology at autopsy: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Pooled it
  7. High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.Investigative ophthalmology & visual science · 2022
    Pooled it
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223 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Thomas W BufordDepartment of Aging and Geriatric Research, University of Florida, Gainesville, FL 32611, USA. Electronic address: tbuford@ufl.edu.

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Stephen D Anton · 2007 to 2026
$22.8M
NIA NIH HHS 2P30AG028740NIA NIH HHS P30 AG028740
6 · The paper itself

Abstract

Hypertension is a highly prevalent condition with numerous health risks, and the incidence of hypertension is greatest among older adults. Traditional discussions of hypertension have largely focused on the risks for cardiovascular disease and associated events. However, there are a number of collateral effects, including risks for dementia, physical disability, and falls/fractures which are increasingly garnering attention in the hypertension literature. Several key mechanisms--including inflammation, oxidative stress, and endothelial dysfunction--are common to biologic aging and hypertension development and appear to have key mechanistic roles in the development of the cardiovascular and collateral risks of late-life hypertension. The objective of the present review is to highlight the multi-dimensional risks of hypertension among older adults and discuss potential strategies for treatment and future areas of research for improving overall care for older adults with hypertension.

Indexed as

Cardiovascular DiseasesEndothelium, VascularHypertensionOxidative StressAgedAgingDisease ManagementHumansInflammationRisk FactorsAntihypertensiveBlood pressureCardiovascularCognitionDisabilityFalls

Identifiers

PMID26835847
PMCPMC4768730

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.