Evidence mapPaperPMID 26839476Full record

Trial reportJournal of Korean medical science2016

Improving Effect of the Acute Administration of Dietary Fiber-Enriched Cereals on Blood Glucose Levels and Gut Hormone Secretion.

Eun Ky Kim, Tae Jung Oh, Lee-Kyung Kim, Young Min Cho

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of Korean medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eun Ky KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0003-3568-3932
Tae Jung OhDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0002-5078-6123
Lee-Kyung KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0003-2376-1948
Young Min ChoDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID 0000-0002-2331-6126
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary fiber improves hyperglycemia in patients with type 2 diabetes through its physicochemical properties and possible modulation of gut hormone secretion, such as glucagon-like peptide 1 (GLP-1). We assessed the effect of dietary fiber-enriched cereal flakes (DC) on postprandial hyperglycemia and gut hormone secretion in patients with type 2 diabetes. Thirteen participants ate isocaloric meals based on either DC or conventional cereal flakes (CC) in a crossover design. DC or CC was provided for dinner, night snack on day 1 and breakfast on day 2, followed by a high-fat lunch. On day 2, the levels of plasma glucose, GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and insulin were measured. Compared to CC, DC intake exhibited a lower post-breakfast 2-hours glucose level (198.5±12.8 vs. 245.9±15.2 mg/dL, P<0.05) and a lower incremental peak of glucose from baseline (101.8±9.1 vs. 140.3±14.3 mg/dL, P<0.001). The incremental area under the curve (iAUC) of glucose after breakfast was lower with DC than with CC (P<0.001). However, there were no differences in the plasma insulin, glucagon, GLP-1, and GIP levels. In conclusion, acute administration of DC attenuates postprandial hyperglycemia without any significant change in the representative glucose-regulating hormones in patients with type 2 diabetes (ClinicalTrials.gov. NCT 01997281).

Indexed as

AdultAgedArea Under CurveBlood GlucoseCross-Over StudiesDiabetes Mellitus, Type 2Dietary FiberFemaleGastric Inhibitory PolypeptideGlucagonGlucagon-Like Peptide 1Glycated HemoglobinHumansHyperglycemiaInsulinIntestinal MucosaBlood GlucoseDietary FiberGastric Inhibitory PolypeptideGlucagonGlucagon-Like Peptide 1Glycated Hemoglobinhemoglobin A1c protein, humanInsulinDiabetes Mellitus, Type 2Dietary FiberIncretins, Glucagon-like Peptide 1

Identifiers

PMID26839476
PMCPMC4729502
OpenAlexW2264245191

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.