ArticleWiener medizinische Wochenschrift (1946)2016
Polypharmacy, potentially inappropriate medication and cognitive status in Austrian nursing home residents: results from the OSiA study.
Article in Wiener medizinische Wochenschrift (1946), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Identifying potentially inappropriate prescribing in older people with dementia: a systematic review.European journal of clinical pharmacology · 2019Pooled it
- Economic, cultural and social inequalities in potentially inappropriate medication-An Austrian perspective.Wiener klinische Wochenschrift · 2026Article
- Medication-related infrastructure and medication reviews in nursing homes-a rapid appraisal study.BMC health services research · 2025Article
- Evaluation of an intervention to improve the safety of medication therapy via HIT-supported interprofessional cooperation in long-term care - a mixed method study.BMC health services research · 2022Article
- Utilization of potentially inappropriate medication and risk of adverse drug events among older adults with chronic renal insufficiency: a population-wide cohort study.BMC geriatrics · 2021Article
- Prescription Medications and Co-Morbidities in Late Middle-Age are Associated with Greater Cognitive Declines: Results from WRAP.Frontiers in aging · 2021Article
- Improving medication appropriateness in nursing homes via structured interprofessional medication-review supported by health information technology: a non-randomized controlled study.BMC geriatrics · 2020Article
- Polypharmacy Is Associated with Lower Memory Function in African American Older Adults.Brain sciences · 2020Article
- Is Polypharmacy Associated with Cognitive Frailty in the Elderly? Results from the Korean Frailty and Aging Cohort Study.The journal of nutrition, health & aging · 2019Article
- Article
- Polypharmacy in palliative care-COPD and multimorbidity : A case report.Wiener medizinische Wochenschrift (1946) · 2018Article
- Prevalence and determinants of polypharmacy in Switzerland: data from the CoLaus study.BMC health services research · 2017Article
- Prescription of potentially inappropriate medications among older people with intellectual disability: a register study.BMC pharmacology & toxicology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is little research investigating polypharmacy and potentially inappropriate medications (PIM) in connection with cognitive status in residents of Austrian nursing homes. Our findings result from a cross-sectional survey of 425 residents (315 women, 110 men, mean 83.6 years) from 12 Austrian nursing homes. The number of systemically administered permanent prescription drugs was 8.99 ± 3.9 and decreased significantly with increasing cognitive impairment. Irrespective of cognitive status, polypharmacy (> 5 individual substances) was present in approximately 75% of the residents. Hyper-polypharmacy (> 10 individual substances) was present among almost 50% of the cognitively intact residents, and hence, significantly more frequent as compared with the group with the lowest cognitive performance (23.4%). At least one PIM was found in 72.4% of residents regardless of cognitive status. Predominantly, PIMs consisted of tranquilizers, antipsychotics, osmotic laxatives, non-steroidal anti-inflammatory drugs (NSAIDs) and anticholinergics, where only the number of NSAIDs decreased significantly with increasing cognitive impairment. In summary, our study shows a continued high prevalence of polypharmacy and PIM in long-term care institutions in Austria.
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