Evidence map›Paper›PMID 26847713›Full record

ArticleJournal of diabetes2017

Diabetes, hyperglycemia, and the burden of functional disability among older adults in a community-based study.

Job G Godino, Lawrence J Appel, Alden L Gross, Jennifer A Schrack, Christina M Parrinello, Rita R Kalyani, Beverly Gwen Windham, James S Pankow, Stephen B Kritchevsky, Karen Bandeen-Roche and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

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  12. Diabetes and impaired fasting glucose in a population-based sample of individuals aged 75 + years: associations with cognition, major depressive disorder, functionality and quality of life-the Pietà study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Job G GodinoDepartments of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Lawrence J AppelWelch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA.
Alden L GrossDepartments of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Jennifer A SchrackDepartments of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Christina M ParrinelloDepartments of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Rita R KalyaniThe Johns Hopkins Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA.
Beverly Gwen WindhamDivision of Geriatric Medicine, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
James S PankowDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Stephen B KritchevskyDepartment of Internal Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.
Karen Bandeen-RocheThe Johns Hopkins Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA.
Elizabeth SelvinDepartments of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Johns Hopkins University · USJohns Hopkins Medicine · USUniversity of Minnesota · USUniversity of Mississippi Medical Center · USWake Forest University · US

Funding

'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · JOHNS HOPKINS UNIVERSITY · 1985 to 2005
$10.4M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2025 to 2025
$6.6M
The ARIC and Neurocognitive Longitudinal StudyR01HL070825 · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · 2002 to 2004
$5.1M
CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · JOHNS HOPKINS UNIVERSITY · 1985 to 2025
$3.7M
EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · JOHNS HOPKINS UNIVERSITY · 1996 to 2025
$2.8M
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS R01 HL070825NHLBI NIH HHS T32 HL007024NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917NIA NIH HHS K01 AG048765NIA NIH HHS P50 AG005146NIA NIH HHS T32 AG000247NIDDK NIH HHS K23 DK093583NIDDK NIH HHS K24 DK106414NIDDK NIH HHS R01 DK089174
6 · The paper itself

Abstract

backgroundThere is a need for continued surveillance of diabetes-related functional disability. In the present study, we examined associations between diabetes, hyperglycemia, and the burden of functional disability in a community-based population.

methodsA cross-sectional analysis was conducted of 5035 participants who attended Visit 5 (2011-13) of the Atherosclerosis Risk in Communities study. Functional disability was dichotomously defined by any self-reported difficulty performing 12 tasks essential to independent living grouped into four functional domains. Associations of diagnosed diabetes (via self-report) and undiagnosed diabetes and prediabetes (via HbA1c) with functional disability were evaluated using Poisson regression.

resultsParticipants had a mean age of 75 years, 42 % were male, 22 % were Black, and 31 % had diagnosed diabetes. Those with diagnosed diabetes had a significantly greater burden of functional disability than those without diabetes, even after adjustment for demographics, health behaviors, and comorbidities: prevalence ratios (95 % confidence intervals) were 1.24 (1.15, 1.34) for lower extremity mobility, 1.14 (1.07, 1.21) for general physical activities, 1.33 (1.16, 1.52) for instrumental activities of daily living (ADL), and 1.46 (1.24, 1.73) for ADL (all P < 0.05). The associations of undiagnosed diabetes and prediabetes with disability were not statistically significant (all P > 0.05).

conclusionsAmong older adults, the burden of functional disability associated with diabetes was not entirely explained by known risk factors, including comorbidities. Hyperglycemia below the threshold for the diagnosis of diabetes was not associated with disability. Research into effective strategies for the prevention of functional disability among older adults with diabetes is needed.

Indexed as

Persons with DisabilitiesActivities of Daily LivingAgedBlood GlucoseDiabetes MellitusFemaleHumansHyperglycemiaMaleBlood GlucoseAgingdiabetes complicationsdisabilityphysical functionprevalence

Identifiers

PMID26847713
PMCPMC4975681
OpenAlexW2342170144

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.