Trial reportAJNR. American journal of neuroradiology2016
Multicenter Prospective Trial of Stent Placement in Patients with Symptomatic High-Grade Intracranial Stenosis.
Trial report in AJNR. American journal of neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 5 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis.The Cochrane database of systematic reviews · 2023Pooled it
- Endovascular Therapy for Symptomatic Intracranial Artery Stenosis: a Systematic Review and Network Meta-analysis.Translational stroke research · 2022Pooled it
- Intracranial Angioplasty with Enterprise Stent for Intracranial Atherosclerotic Stenosis: A Single-Center Experience and a Systematic Review.BioMed research international · 2021Pooled it
- Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis.The Cochrane database of systematic reviews · 2020Pooled it
- Current Status and Future Perspective of Stenting for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis.BioMed research international · 2017Pooled it
- Effect of Stenting Plus Medical Therapy vs Medical Therapy Alone on Risk of Stroke and Death in Patients With Symptomatic Intracranial Stenosis: The CASSISS Randomized Clinical Trial.JAMA · 2022 · on this mapTrial
- Percutaneous Transluminal Angioplasty and Stenting for Symptomatic Intracranial Stenosis After SAMMPRIS: Patient Selection and Clinical Outcomes.Journal of clinical medicine · 2026Article
- Endovascular Therapy for Intracranial Atherosclerotic Stenosis: Evidence and Controversies.Journal of neuroendovascular therapy · 2026Review
- Feasibility Exploration of High-Resolution MRI Plaque Features for Assessing Outcomes of Intracranial Angioplasty and Stenting in Ischemic Stroke Patients.Revista de neurologia · 2025Article
- Higher Time to Peak after Stent Implantation in Symptomatic High-Grade Intracranial Atherosclerotic Stenosis is Related to In-Stent Restenosis.Translational stroke research · 2025Article
- Impact of Stenosis Degree on Outcomes of Stent Placement versus Medical Treatment Alone for Symptomatic Intracranial Stenosis: A Pooled Individual Patient Data Analysis.AJNR. American journal of neuroradiology · 2025Article
- Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy.Nature communications · 2025Article
- Enterprise 2 stent outcomes in hyperacute ischemic stroke with intracranial artery stenosis.Neuroradiology · 2025Article
- Mortality-Related Factors and 1-Year Survival in Patients After Intracranial Stenting for Intracranial Arterial Critical Stenosis and Occlusion.Medicina (Kaunas, Lithuania) · 2025Article
- Intracranial stenting compared to medical treatment alone for intracranial atherosclerosis patients: An updated meta-analysis.Journal of cerebrovascular and endovascular neurosurgery · 2024Article
- Randomized Secondary Prevention Trials in Participants With Symptomatic Intracranial Atherosclerotic Stenosis.Stroke · 2024Review
- Endovascular Treatment in Symptomatic Intracranial Artery Stenosis: Experience from Two Centers.Sisli Etfal Hastanesi tip bulteni · 2024Article
- Short-term outcome of stenting with Enterprise stents for symptomatic intracranial atherosclerotic disease at a single center.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023Article
- A novel cerebrovascular drug-coated balloon catheter for treating symptomatic intracranial atherosclerotic stenosis lesions: Study protocol for a prospective, multicenter, single-arm, target-value clinical trial.Journal of interventional medicine · 2023Article
- Angioplasty And stenting For symptomatic intracranial atherosclerotic disease: How I Do It.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeOn the basis of the high 1-month stroke and/or death (14.7%) rates associated with stent placement in the Stenting versus Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis trial, modifications in patient selection and procedural aspects for intracranial stent placement have been recommended. We performed a multicenter prospective single-arm trial to determine whether such modifications would result in lower rates of periprocedural stroke and/or death. MATERIALS AND
methodsThe study enrolled patients with recent transient ischemic attack or ischemic stroke (excluding perforator ischemic events) related to high-grade (70%-99% in severity) stenosis of a major intracranial artery. Patients were treated by using angioplasty and self-expanding stents 3 weeks after the index ischemic event at 1 of the 10 high-volume centers in China. An independent neurologist ascertained the occurrence of any stroke and/or death within 1 month after the procedure.
resultsA total of 100 consecutive patients were recruited. The target lesions were located in the middle cerebral artery (M1) (n = 38, 38%), intracranial internal carotid artery (n = 17, 17%), intradural vertebral artery (n = 18, 18%), and basilar artery (n = 27, 27%). The technical success rate of stent deployment with residual stenosis of <50% was 100%. The overall 1-month stroke and/or death rate was 2% (95% confidence interval, 0.2%-7.0%). Two ischemic strokes occurred in the pontine region (perforator distribution) in patients following angioplasty and stent placement for basilar artery stenosis.
conclusionsThe results of this prospective multicenter study demonstrated that modifications in patient selection and procedural aspects can substantially reduce the 1-month stroke and/or death rate following intracranial stent placement.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.