Evidence map›Paper›PMID 26969094›Full record

SynthesisJournal of behavioral medicine2016

Blood pressure outcomes of medication adherence interventions: systematic review and meta-analysis.

Vicki S Conn, Todd M Ruppar, Jo-Ana D Chase

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of behavioral medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Brazilian Guidelines of Hypertension - 2020.Arquivos brasileiros de cardiologia · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Adherence to Antihypertensive Therapy.The Medical clinics of North America · 2017
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vicki S ConnSchool of Nursing, University of Missouri, S317 Sinclair Building, Columbia, MO, 65211, USA. conn@missouri.edu.
Todd M RupparUniversity of Missouri, S423 Sinclair Building, Columbia, MO, 65211, USA.
Jo-Ana D ChaseUniversity of Missouri, S343 Sinclair Building, Columbia, MO, 65211, USA.
University of Missouri · US

Funding

Individualized Care for At Risk Older AdultsT32NR009356 · NINR · UNIVERSITY OF PENNSYLVANIA · PI Lauren M Massimo, MARY D NAYLOR · 2007 to 2026
$7.8M
Meta-Analysis of Interventions to Improve Medication AdherenceR01NR011990 · NINR · UNIVERSITY OF MISSOURI-COLUMBIA · PI CONN, VICKI S · 2010 to 2013
$1.7M
NINR NIH HHS R01 NR011990NINR NIH HHS T32 NR009356
6 · The paper itself

Abstract

This systematic review applied meta-analytic procedures to integrate primary research that examined blood pressure outcomes of medication adherence interventions. Random-effects model analysis calculated standardized mean difference effect sizes. Exploratory dichotomous and continuous moderator analyses using meta-analytic analogues of ANOVA and regression were performed. Codable data were extracted from 156 reports with 60,876 participants. The overall weighted mean difference systolic effect size was 0.235 across 161 treatment versus control comparisons. The diastolic effect size was 0.189 from 181 comparisons. Effect sizes were significantly heterogeneous. Common risks of bias included lack of allocation concealment, unmasked data collectors, and absent intention-to-treat analyses. Exploratory moderator analyses suggested that habit-based interventions may be most effective. The largest effect sizes were for interventions delivered by pharmacists. The modest magnitude effect sizes suggest future research should explore novel higher dose interventions that might address multiple levels of influence on adherence behavior.

Indexed as

Blood PressureHumansMedication AdherenceTreatment OutcomeBlood pressureMedication adherenceMeta-analysis

Identifiers

PMID26969094
PMCPMC5018410
OpenAlexW2295599367

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.