Evidence map›Paper›PMID 26979509›Full record

ReviewHerz2016

[Thrombus aspiration in patients with acute myocardial infarction : Scientific evidence and guideline recommendations].

T Stiermaier, S de Waha, G Fürnau, I Eitel, H Thiele, S Desch

Abstract readReview
PubMed Publisher
In one paragraph

Review in Herz, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

T StiermaierUniversitäres Herzzentrum Lübeck, Medizinische Klinik II (Kardiologie/Angiologie/Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Deutschland. thomas.stiermaier@uksh.de.
S de WahaUniversitäres Herzzentrum Lübeck, Medizinische Klinik II (Kardiologie/Angiologie/Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
G FürnauUniversitäres Herzzentrum Lübeck, Medizinische Klinik II (Kardiologie/Angiologie/Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
I EitelUniversitäres Herzzentrum Lübeck, Medizinische Klinik II (Kardiologie/Angiologie/Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
H ThieleUniversitäres Herzzentrum Lübeck, Medizinische Klinik II (Kardiologie/Angiologie/Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
S DeschUniversitäres Herzzentrum Lübeck, Medizinische Klinik II (Kardiologie/Angiologie/Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
University Hospital Schleswig-Holstein · DEUniversitäres Kinderwunschzentrum Lübeck · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in percutaneous coronary intervention and antiplatelet therapy as well as faster door-to-balloon times have markedly improved the therapy of patients with acute myocardial infarction. However, impaired myocardial perfusion despite revascularization of the infarcted vessel remains an ongoing problem with high prognostic relevance. In initial clinical trials thrombus aspiration in addition to conventional percutaneous coronary intervention demonstrated benefits regarding coronary flow and myocardial perfusion and was therefore recommended in practice guidelines. These improvements in surrogate endpoints did not translate into a favorable clinical outcome in recent large-scale multicenter randomized trials investigating the routine use of thrombus aspiration in patients with acute myocardial infarction. Furthermore, an increased risk of stroke after thrombus aspiration raises safety concerns. Therefore, thrombus aspiration has been downgraded in the recent guideline updates. The current article reviews the evidence from clinical trials and the recommendations in practice guidelines regarding thrombus aspiration in acute myocardial infarction.

Indexed as

Combined Modality TherapyComorbidityEvidence-Based MedicineHumansMyocardial InfarctionPercutaneous Coronary InterventionPractice Guidelines as TopicPrevalenceRisk FactorsSuctionSurvival RateThrombectomyThrombosisTreatment OutcomeAcute myocardial infarctionMyocardial perfusionNo-reflow phenomenonPercutaneous coronary interventionThrombus aspiration

Identifiers

PMID26979509
OpenAlexW2314930563

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.