Evidence map›Paper›PMID 26989512›Full record

ArticleJournal of lipids2016

Serum Fatty Acids, Traditional Risk Factors, and Comorbidity as Related to Myocardial Injury in an Elderly Population with Acute Myocardial Infarction.

Kristian Laake, Ingebjørg Seljeflot, Erik B Schmidt, Peder Myhre, Arnljot Tveit, Harald Arnesen, Svein Solheim

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of lipids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 5 pooled it
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kristian LaakeCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, 0450 Oslo, Norway; Faculty of Medicine, University of Oslo, 0316 Oslo, Norway; Center for Heart Failure Research, University of Oslo, 0316 Oslo, Norway.ORCID 0000-0003-2925-0823
Ingebjørg SeljeflotCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, 0450 Oslo, Norway; Faculty of Medicine, University of Oslo, 0316 Oslo, Norway; Center for Heart Failure Research, University of Oslo, 0316 Oslo, Norway.
Erik B SchmidtDepartment of Cardiology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Peder MyhreCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, 0450 Oslo, Norway; Center for Heart Failure Research, University of Oslo, 0316 Oslo, Norway; Department of Cardiology, Akershus University Hospital HF, 1478 Lørenskog, Norway.
Arnljot TveitDepartment of Medical Research, Vestre Viken Hospital Trust, Bærum Hospital, 1346 Rud, Norway.
Harald ArnesenCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, 0450 Oslo, Norway; Faculty of Medicine, University of Oslo, 0316 Oslo, Norway; Center for Heart Failure Research, University of Oslo, 0316 Oslo, Norway.
Svein SolheimCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, 0450 Oslo, Norway; Center for Heart Failure Research, University of Oslo, 0316 Oslo, Norway.ORCID 0000-0003-3321-6572
Oslo University Hospital · NOAalborg University Hospital · DKVestre Viken Hospital Trust · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Epidemiological and randomized clinical trials indicate that marine polyunsaturated n-3 fatty acids (n-3 PUFAs) may have cardioprotective effects. Aim. Evaluate the associations between serum fatty acid profile, traditional risk factors, the presence of cardiovascular diseases (CVD), and peak Troponin T (TnT) levels in elderly patients with an acute myocardial infarction (AMI). Materials and Methods. Patients (n = 299) consecutively included in the ongoing Omega-3 fatty acids in elderly patients with myocardial infarction (OMEMI) trial were investigated. Peak TnT was registered during the hospital stay. Serum fatty acid analysis was performed 2-8 weeks later. Results. No significant correlations between peak TnT levels and any of the n-3 PUFAs were observed. However, patients with a history of atrial fibrillation had significantly lower docosahexaenoic acid levels than patients without. Significantly lower peak TnT levels were observed in patients with a history of hyperlipidemia, angina, MI, atrial fibrillation, intermittent claudication, and previous revascularization (all p < 0.02). Conclusions. In an elderly population with AMI, no association between individual serum fatty acids and estimated myocardial infarct size could be demonstrated. However, a history of hyperlipidemia and the presence of CVD were associated with lower peak TnT levels, possibly because of treatment with cardioprotective medications.

Identifiers

PMID26989512
PMCPMC4775818
OpenAlexW2279859303

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.