ArticleArquivos brasileiros de cardiologia2016
Correlation of Insulin Resistance with Anthropometric Measures and Blood Pressure in Adolescents.
Article in Arquivos brasileiros de cardiologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Assessment of Machine Learning Model Performance for Clinical Prediction of Insulin Resistance in the Study of Cardiovascular Risk in Adolescents-ERICA.Journal of clinical medicine · 2026Article
- Association of cardiometabolic risk factors with insulin resistance in overweight and obese children.BMC endocrine disorders · 2022Article
- Hypertension and Associated Lipid, Glucose, and Adiposity Parameters in School-Aged Adolescents in the Federal District, Brazil.Arquivos brasileiros de cardiologia · 2022Article
- Impact of Insulin Resistance on Cardiometabolic Risk Factors and an Anthropometry-Based Predictive Nomogram for Insulin Resistance Among Adolescents in China.Frontiers in endocrinology · 2022Article
- The Prevalence of Insulin Resistance and the Associated Risk Factors in a Sample of 14-18-Year-Old Slovak Adolescents.International journal of environmental research and public health · 2021Article
- Article
- The relationship between cardiometabolic risks and vitamin D levels with the degree of obesity.Turk pediatri arsivi · 2019Article
- The Influence of Obesity on Puberty and Insulin Resistance in Mexican Children.International journal of endocrinology · 2018Article
- Cardiometabolic Risk Clustering and Surrogate Markers of Insulin Resistance in Adolescents.International journal of applied & basic medical researchArticle
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Authors and funding
10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBlood pressure is directly related to body mass index, and individuals with increased waist circumference have higher risk of developing hypertension, insulin resistance, and other metabolic changes, since adolescence.
objectiveto evaluate the correlation of blood pressure with insulin resistance, waist circumference and body mass index in adolescents.
methodsCross-section study on a representative sample of adolescent students. One group of adolescents with altered blood pressure detected by casual blood pressure and/or home blood pressure monitoring (blood pressure > 90th percentile) and one group of normotensive adolescents were studied. Body mass index, waist circumference were measured, and fasting glucose and plasma insulin levels were determined, using the HOMA-IR index to identify insulin resistance.
resultsA total of 162 adolescents (35 with normal blood pressure and 127 with altered blood pressure) were studied; 61% (n = 99) of them were boys and the mean age was 14.9 ± 1.62 years. Thirty-eight (23.5%) adolescents had altered HOMA-IR. The group with altered blood pressure had higher values of waist circumference, body mass index and HOMA-IR (p<0.05). Waist circumference was higher among boys in both groups (p<0.05) and girls with altered blood pressure had higher HOMA-IR than boys (p<0.05). There was a significant moderate correlation between body mass index and HOMA-IR in the group with altered blood pressure (ρ = 0.394; p < 0.001), and such correlation was stronger than in the normotensive group. There was also a significant moderate correlation between waist circumference and HOMA-IR in both groups (ρ = 0.345; p < 0.05). Logistic regression showed that HOMA-IR was as predictor of altered blood pressure (odds ratio - OR = 2.0; p = 0.001).
conclusionThere was a significant association of insulin resistance with blood pressure and the impact of insulin resistance on blood pressure since childhood. The correlation and association between markers of cardiovascular diseases was more pronounced in adolescents with altered blood pressure, suggesting that primary prevention strategies for cardiovascular risk factors should be early implemented in childhood and adolescence.
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