Evidence map›Paper›PMID 27070555›Full record

ArticlePloS one2016

Development and Validation of a Risk-Score Model for Type 2 Diabetes: A Cohort Study of a Rural Adult Chinese Population.

Ming Zhang, Hongyan Zhang, Chongjian Wang, Yongcheng Ren, Bingyuan Wang, Lu Zhang, Xiangyu Yang, Yang Zhao, Chengyi Han, Chao Pang and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Ming ZhangDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Hongyan ZhangDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Chongjian WangDepartment of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Yongcheng RenDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Bingyuan WangDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Lu ZhangDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Xiangyu YangDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Yang ZhaoDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Chengyi HanDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Chao PangDepartment of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, Henan, People's Republic of China.
Lei YinDepartment of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, Henan, People's Republic of China.
Yuan XueDepartment of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.
Jingzhi ZhaoDepartment of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, Henan, People's Republic of China.
Dongsheng HuDepartment of Preventive Medicine, Shenzhen University School of Medicine, Shenzhen, Guangdong, People's Republic of China.
Shenzhen University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some global models to predict the risk of diabetes may not be applicable to local populations. We aimed to develop and validate a score to predict type 2 diabetes mellitus (T2DM) in a rural adult Chinese population. Data for a cohort of 12,849 participants were randomly divided into derivation (n = 11,564) and validation (n = 1285) datasets. A questionnaire interview and physical and blood biochemical examinations were performed at baseline (July to August 2007 and July to August 2008) and follow-up (July to August 2013 and July to October 2014). A Cox regression model was used to weigh each variable in the derivation dataset. For each significant variable, a score was calculated by multiplying β by 100 and rounding to the nearest integer. Age, body mass index, triglycerides and fasting plasma glucose (scores 3, 12, 24 and 76, respectively) were predictors of incident T2DM. The model accuracy was assessed by the area under the receiver operating characteristic curve (AUC), with optimal cut-off value 936. With the derivation dataset, sensitivity, specificity and AUC of the model were 66.7%, 74.0% and 0.768 (95% CI 0.760-0.776), respectively. With the validation dataset, the performance of the model was superior to the Chinese (simple), FINDRISC, Oman and IDRS models of T2DM risk but equivalent to the Framingham model, which is widely applicable in a variety of populations. Our model for predicting 6-year risk of T2DM could be used in a rural adult Chinese population.

Indexed as

AdultAsian PeopleBlood GlucoseBody Mass IndexCohort StudiesDiabetes Mellitus, Type 2FemaleGlucose Tolerance TestHumansMaleMiddle AgedOmanRisk FactorsROC CurveRural PopulationSensitivity and SpecificityBlood GlucoseTriglycerides

Identifiers

PMID27070555
PMCPMC4829145
OpenAlexW2339542411

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.