ArticleNutrients2016
Lactobacillus plantarum TWK10 Supplementation Improves Exercise Performance and Increases Muscle Mass in Mice.
Article in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
166 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effects ofFrontiers in nutrition · 2026Pooled it
- The effects of probiotic supplementation on body composition, recovery following exercise-induced muscle damage, and exercise performance: A systematic review and meta-analysis of clinical trials.Physiological reports · 2025Pooled it
- Efficacy of probiotic supplements in the treatment of sarcopenia: A systematic review and meta-analysis.PloS one · 2025Pooled it
- "Do probiotics mitigate GI-induced inflammation and perceived fatigue in athletes? A systematic review".Journal of the International Society of Sports Nutrition · 2024Pooled it
- Impact of probiotics on muscle mass, muscle strength and lean mass: a systematic review and meta-analysis of randomized controlled trials.Journal of cachexia, sarcopenia and muscle · 2023Pooled it
- Pooled it
- Understanding the gut microbiota and sarcopenia: a systematic review.Journal of cachexia, sarcopenia and muscle · 2021Pooled it
- From Gut to Skeletal Muscle: Synergistic Effects of Probiotics and Spirulina Supplementation on Soccer Players' Performance and Body Composition.Probiotics and antimicrobial proteins · 2026Trial
- Pre-sleep casein ingestion with probiotic strains improves anaerobic power and lower-body-specific strength and power performance in soccer players.Journal of the International Society of Sports Nutrition · 2025Trial
- The effects of plyometric training with speed and weight overloads on volleyball players' strength, power, and jumping performance.PloS one · 2025Trial
- Effects of probiotic supplementation with high-intensity interval training on cardiorespiratory endurance and metabolism in Middle-Aged Obese Women.Journal of the International Society of Sports Nutrition · 2024Trial
- The effect of probiotics and casein supplementation on aerobic capacity parameters of male soccer players.Journal of the International Society of Sports Nutrition · 2024Trial
- PasteurizedNutrients · 2024Trial
- Eight Weeks ofNutrients · 2023Trial
- Effect of Daily OralNutrients · 2021Trial
- The effect of probiotic supplementation on performance, inflammatory markers and gastro-intestinal symptoms in elite road cyclists.Journal of the International Society of Sports Nutrition · 2021Trial
- Effect ofNutrients · 2019Trial
- Anti-Fatigue Effects of Yogurt Fermented withNutrients · 2018Trial
- The Importance of the Gut-Muscle Axis: From Mechanistic Insights in Cell Culture and Rodent Models to Descriptive and Associative Evidence in Livestock.Animals : an open access journal from MDPI · 2026Review
- Preservation of Antioxidant and Immunomodulatory Properties in a Heat-Treated Probiotic Blend: Insights from Preclinical Models.Microorganisms · 2026Article
106 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactobacillus plantarum (L. plantarum) is a well-known probiotic among the ingested-microorganism probiotics (i.e., ingested microorganisms associated with beneficial effects for the host). However, few studies have examined the effects of L. plantarum TWK10 (LP10) supplementation on exercise performance, physical fatigue, and gut microbial profile. Male Institute of Cancer Research (ICR) strain mice were divided into three groups (n = 8 per group) for oral administration of LP10 for six weeks at 0, 2.05 × 10⁸, or 1.03 × 10⁹ colony-forming units/kg/day, designated the vehicle, LP10-1X and LP10-5X groups, respectively. LP10 significantly decreased final body weight and increased relative muscle weight (%). LP10 supplementation dose-dependently increased grip strength (p < 0.0001) and endurance swimming time (p < 0.001) and decreased levels of serum lactate (p < 0.0001), ammonia (p < 0.0001), creatine kinase (p = 0.0118), and glucose (p = 0.0151) after acute exercise challenge. The number of type I fibers (slow muscle) in gastrocnemius muscle significantly increased with LP10 treatment. In addition, serum levels of albumin, blood urea nitrogen, creatinine, and triacylglycerol significantly decreased with LP10 treatment. Long-term supplementation with LP10 may increase muscle mass, enhance energy harvesting, and have health-promotion, performance-improvement, and anti-fatigue effects.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.