Evidence map›Paper›PMID 27091444›Full record

ReviewCurrent diabetes reports2016

Longer-Term Physiological and Metabolic Effects of Gastric Bypass Surgery.

J David Mosinski, John P Kirwan

Abstract readReview
In one paragraph

Review in Current diabetes reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

J David MosinskiDepartment of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
John P KirwanDepartment of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA. kirwanj@ccf.org.

Funding

Effect of Bariatric Surgery on Mechanisms of Type 2 Diabetes: The B2D TrialR01DK089547 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI KASHYAP, SANGEETA R, KIRWAN, JOHN P. · 2010 to 2013
$1.9M
NIDDK NIH HHS R01 DK089547
6 · The paper itself

Abstract

Obesity is closely associated with the development of type 2 diabetes. Many strategies have been used in the past to combat these two conditions, but very few provide for stable and durable glycemic control. Bariatric surgery has emerged as a powerful tool for treating obesity and in over 70 % of cases provides a short-term cure for diabetes. While the acute metabolic effects of surgery are striking, it remains important for us to also consider the long-term effects. This review aims to summarize the chronic or long-term metabolic and physiological effects of Roux-en-Y gastric bypass (RYGB) surgery on pancreatic function, skeletal muscle and hepatic insulin sensitivity, and gastrointestinal remodeling. An increased understanding of the current state of research in these areas can provide the basis for stimulating further research that would contribute to new treatment and management strategies for obesity and diabetes.

Indexed as

Gastric BypassAnimalsBlood GlucoseDiabetes MellitusHumansInsulin ResistanceInsulin-Secreting CellsObesityBlood GlucoseBeta cell functionDiabetesGastric bypassInsulin resistanceObesity

Identifiers

PMID27091444
PMCPMC5206659

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.