ArticleEnvironmental health and preventive medicine2016
Serum triglyceride levels in relation to high-density lipoprotein cholesterol (TG-HDL) ratios as an efficient tool to estimate the risk of sleep apnea syndrome in non-overweight Japanese men.
Article in Environmental health and preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Composite lipid indices in patients with obstructive sleep apnea: a systematic review and meta-analysis.Lipids in health and disease · 2023Pooled it
- Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and atherogenic index of plasma with obstructive sleep apnea.Frontiers in psychiatry · 2025Article
- Association of cardiometabolic index with sleep quality in adults: a population‑based study.Scientific reports · 2024Article
- Association between the triglyceride glucose index and obstructive sleep apnea and its symptoms: results from the NHANES.Lipids in health and disease · 2024Article
- Association between nontraditional lipid profiles and the severity of obstructive sleep apnea: A retrospective study.Journal of clinical laboratory analysis · 2023Article
- Obstructive Sleep Apnoea and Lipid Metabolism: The Summary of Evidence and Future Perspectives in the Pathophysiology of OSA-Associated Dyslipidaemia.Biomedicines · 2022Review
- Comparison of Composite Lipid Indices in Patients with Obstructive Sleep Apnoea.Nature and science of sleep · 2022Article
- Atherogenic Index of Plasma in Obstructive Sleep Apnoea.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSeveral studies have reported the association between sleep apnea syndrome and insulin resistance. Being overweight is known risk factor both for sleep apnea syndrome and insulin resistance. However, no studies have reported on the association between serum triglyceride levels in relation to high-density lipoprotein cholesterol (TG-HDL) ratios (a marker of insulin resistance) and sleep apnea syndrome accounting for body mass index (BMI) status.
methodsSubjects for the present cross-sectional study consisted of 1,528 men aged 30-69 years undergoing pulse oximetry at a sleep disorders clinic for sleep apnea syndrome. Sleep apnea syndrome was diagnosed as a 3 % oxygen desaturation index (ODI) of ≥15 events/h.
resultsAmong study participants, 241 men were diagnosed with sleep apnea syndrome. Independent of classical cardiovascular risk factors, TG-HDL was significantly positively associated with sleep apnea syndrome in participants with a BMI <25 kg/m
conclusionsAn independent positive association between TG-HDL levels and risk of sleep apnea syndrome was observed in participants with a BMI of <25 kg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.