Evidence map›Paper›PMID 27123263›Full record

ArticleMolecular and clinical oncology2016

Immunoglobulin gene translocations in chronic lymphocytic leukemia: A report of 35 patients and review of the literature.

Marc DE Braekeleer, Corine Tous, Nadia Guéganic, Marie-Josée LE Bris, Audrey Basinko, Frédéric Morel, Nathalie Douet-Guilbert

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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  8. Role of cytogenetic abnormalities detected by fluorescenceThe Indian journal of medical research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marc DE BraekeleerFaculty of Medicine and Health Sciences, University of Brest, Brest, France; National Institute of Health and Medical Research (INSERM U1078), Brest, France; Department of Cytogenetics and Reproductive Biology, Morvan Hospital, Regional University Hospital Center of Brest (CHRU), Brest, France.
Corine TousDepartment of Cytogenetics and Reproductive Biology, Morvan Hospital, Regional University Hospital Center of Brest (CHRU), Brest, France.
Nadia GuéganicFaculty of Medicine and Health Sciences, University of Brest, Brest, France; National Institute of Health and Medical Research (INSERM U1078), Brest, France.
Marie-Josée LE BrisDepartment of Cytogenetics and Reproductive Biology, Morvan Hospital, Regional University Hospital Center of Brest (CHRU), Brest, France.
Audrey BasinkoNational Institute of Health and Medical Research (INSERM U1078), Brest, France; Department of Cytogenetics and Reproductive Biology, Morvan Hospital, Regional University Hospital Center of Brest (CHRU), Brest, France.
Frédéric MorelFaculty of Medicine and Health Sciences, University of Brest, Brest, France; National Institute of Health and Medical Research (INSERM U1078), Brest, France; Department of Cytogenetics and Reproductive Biology, Morvan Hospital, Regional University Hospital Center of Brest (CHRU), Brest, France.
Nathalie Douet-GuilbertFaculty of Medicine and Health Sciences, University of Brest, Brest, France; National Institute of Health and Medical Research (INSERM U1078), Brest, France; Department of Cytogenetics and Reproductive Biology, Morvan Hospital, Regional University Hospital Center of Brest (CHRU), Brest, France.
Université de Bretagne Occidentale · FRCentre Hospitalier Régional Universitaire de Brest · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lymphocytic leukemia (CLL) represents the most common hematological malignancy in Western countries, with a highly heterogeneous clinical course and prognosis. Translocations involving the immunoglobulin (IG) genes are regularly identified. From 2000 to 2014, we identified an IG gene translocation in 18 of the 396 patients investigated at diagnosis (4.6%) and in 17 of the 275 analyzed during follow-up (6.2%). A total of 4 patients in whom the IG translocation was identified at follow-up did not carry the translocation at diagnosis. The IG heavy locus (

Indexed as

chronic lymphocytic leukemiaimmunoglobulintranslocation

Identifiers

PMID27123263
PMCPMC4840758
OpenAlexW2281508378

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.