Evidence map›Paper›PMID 27142426›Full record

ReviewNutrition journal2016

Nutritional immunology: function of natural killer cells and their modulation by resveratrol for cancer prevention and treatment.

Christian Leischner, Markus Burkard, Matthias M Pfeiffer, Ulrich M Lauer, Christian Busch, Sascha Venturelli

Open access · goldAbstract readReview
In one paragraph

Review in Nutrition journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Phytochemicals as Immunomodulatory Agents in Melanoma.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. The anti-Frontiers in veterinary science · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Postulated Adjuvant Therapeutic Strategies for COVID-19.Journal of personalized medicine · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Christian LeischnerDepartment of Internal Medicine I, Medical University Hospital, Otfried-Mueller-Str. 27, Tuebingen, Germany.
Markus BurkardDepartment of Internal Medicine I, Medical University Hospital, Otfried-Mueller-Str. 27, Tuebingen, Germany.
Matthias M PfeifferDepartment of Pediatric Hematology and Oncology, University Children's Hospital, Tuebingen, Germany.
Ulrich M LauerDepartment of Internal Medicine I, Medical University Hospital, Otfried-Mueller-Str. 27, Tuebingen, Germany.
Christian BuschDivision of Dermatologic Oncology, Department of Dermatology and Allergology, University of Tuebingen, Tuebingen, Germany.
Sascha VenturelliDepartment of Internal Medicine I, Medical University Hospital, Otfried-Mueller-Str. 27, Tuebingen, Germany. sascha.venturelli@med.uni-tuebingen.de.
University of Tübingen · DEUniversity Children's Hospital Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells as part of the innate immune system represent the first line of defence against (virus-) infected and malignantly transformed cells. The emerging field of nutritional immunology focuses on compounds featuring immune-modulating activities in particular on NK cells, which e.g. can be exploited for cancer prevention and treatment. The plant-based nutrition resveratrol is a ternary hydroxylated stilbene, which is present in many foods and beverages, respectively. In humans it comprises a large variety of distinct biological activities. Interestingly, resveratrol strongly modulates the immune response including the activity of NK cells. This review will give an overview on NK cell functions and summarize the resveratrol-mediated modulation thereof.

Indexed as

Antineoplastic Agents, PhytogenicDietHumansKiller Cells, NaturalNeoplasmsNutritional Physiological PhenomenaPlants, EdibleResveratrolStilbenesAntineoplastic Agents, PhytogenicResveratrolStilbenesImmune modulationInnate immune systemNK cell activityNutritional immunologyResveratrol

Identifiers

PMID27142426
PMCPMC4855330
OpenAlexW2346787384

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.