Evidence map›Paper›PMID 27158199›Full record

ReviewWorld journal of gastroenterology2016

Recent developments and innovations in gastric cancer.

Mehmet Mihmanli, Enver Ilhan, Ufuk Oguz Idiz, Ali Alemdar, Uygar Demir

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  12. Ferroptosis and its Role in Gastric Cancer.Frontiers in cell and developmental biology · 2022
    Review
  13. Article
  14. Article
  15. Review
  16. Article
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  18. miR-301-3p directly regulatesThe Journal of international medical research · 2021
    Article
  19. Downregulating circRNA_0044516 Inhibits Cell Proliferation in Gastric Cancer Through miR-149/Wnt1/β-catenin Pathway.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehmet MihmanliMehmet Mihmanli, Ufuk Oguz Idiz, Uygar Demir, Department of General Surgery, Sisli Etfal Training and Research Hospital, Istanbul 34371, Turkey.
Enver IlhanMehmet Mihmanli, Ufuk Oguz Idiz, Uygar Demir, Department of General Surgery, Sisli Etfal Training and Research Hospital, Istanbul 34371, Turkey.
Ufuk Oguz IdizMehmet Mihmanli, Ufuk Oguz Idiz, Uygar Demir, Department of General Surgery, Sisli Etfal Training and Research Hospital, Istanbul 34371, Turkey.
Ali AlemdarMehmet Mihmanli, Ufuk Oguz Idiz, Uygar Demir, Department of General Surgery, Sisli Etfal Training and Research Hospital, Istanbul 34371, Turkey.
Uygar DemirMehmet Mihmanli, Ufuk Oguz Idiz, Uygar Demir, Department of General Surgery, Sisli Etfal Training and Research Hospital, Istanbul 34371, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer has an important place in the worldwide incidence of cancer and cancer-related deaths. It can metastasize to the lymph nodes in the early stages, and lymph node metastasis is an important prognostic factor. Surgery is a very important part of gastric cancer treatment. A D2 lymphadenectomy is the standard surgical treatment for cT1N+ and T2-T4 cancers, which are potentially curable. Recently, the TNM classification system was reorganized, and the margins for gastrectomy and lymphadenectomy were revised. Endoscopic, laparoscopic and robotic treatments of gastric cancer have progressed rapidly with development of surgical instruments and techniques, especially in Eastern countries. Different endoscopic resection techniques have been identified, and these can be divided into two main categories: endoscopic mucosal resection and endoscopic submucosal dissection. Minimally invasive surgery has been reported to be safe and effective for early gastric cancer, and it can be successfully applied to advanced gastric cancer with increasing experience. Cytoreductive surgery and hyperthermıc intraperıtoneal chemotherapy were developed as a combined treatment modality from the results of experimental and clinical studies. Also, hyperthermia increases the antitumor activity and penetration of chemotherapeutics. Trastuzumab which is a monoclonal antibody interacts with human epidermal growth factor (HER) 2 and is related to gastric carcinoma. The anti-tumor mechanism of trastuzumab is not clearly known, but mechanisms such as interruption of the HER2-mediated cell signaling pathways and cell cycle progression have been reported previously. H. pylori is involved in 90% of all gastric malignancies and Japanese guidelines strongly recommend that all H. pylori infections should be eradicated regardless of the associated disease. In this review, we present innovations discussed in recent studies.

Indexed as

Combined Modality TherapyCytoreduction Surgical ProceduresGastrectomyGastric MucosaGastroscopyHumansLymph Node ExcisionMinimally Invasive Surgical ProceduresNeoplasm StagingRobotic Surgical ProceduresStomach NeoplasmsCancerEndoscopic mucosal resectionEndoscopic submucosal resectionGastricHuman epidermal growth factor receptor 2Minimally invasive surgeryNeoadjuvant chemotherapy

Identifiers

PMID27158199
PMCPMC4853688

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.