Evidence map›Paper›PMID 27255115›Full record

ReviewHerz2017

[Computed tomography in patients with chronic stable angina : Fractional flow reserve measurement].

M Renker, U J Schoepf, T Becher, N Krampulz, W Kim, A Rolf, H Möllmann, C W Hamm, T Henzler, M Borggrefe and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Herz, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

M RenkerAbteilung für Kardiologie, Kerckhoff-Klinik, Bad Nauheim, Deutschland. matthias.renker@web.de.
U J SchoepfHeart & Vascular Center, Medical University of South Carolina, Charleston, SC, USA.
T BecherI.Medizinische Klinik, Abteilung für Kardiologie, Pneumologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum Mannheim, Universität Heidelberg und DZHK (Deutsches Zentrum für Herz-Kreislaufforschung), Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
N KrampulzI.Medizinische Klinik, Abteilung für Kardiologie, Pneumologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum Mannheim, Universität Heidelberg und DZHK (Deutsches Zentrum für Herz-Kreislaufforschung), Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
W KimAbteilung für Kardiologie, Kerckhoff-Klinik, Bad Nauheim, Deutschland.
A RolfAbteilung für Kardiologie, Kerckhoff-Klinik, Bad Nauheim, Deutschland.
H MöllmannKlinik für Innere Medizin I, St.-Johannes-Hospital, Dortmund, Deutschland.
C W HammAbteilung für Kardiologie, Kerckhoff-Klinik, Bad Nauheim, Deutschland.
T HenzlerInstitut für Klinische Radiologie und Nuklearmedizin, Universitätsklinikum Mannheim, Universität Heidelberg, Heidelberg, Deutschland.
M BorggrefeI.Medizinische Klinik, Abteilung für Kardiologie, Pneumologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum Mannheim, Universität Heidelberg und DZHK (Deutsches Zentrum für Herz-Kreislaufforschung), Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
I AkinI.Medizinische Klinik, Abteilung für Kardiologie, Pneumologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum Mannheim, Universität Heidelberg und DZHK (Deutsches Zentrum für Herz-Kreislaufforschung), Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
S BaumannI.Medizinische Klinik, Abteilung für Kardiologie, Pneumologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum Mannheim, Universität Heidelberg und DZHK (Deutsches Zentrum für Herz-Kreislaufforschung), Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary computed tomography angiography (cCTA) has been established for the non-invasive diagnosis of coronary artery disease (CAD). Previous studies demonstrated the high diagnostic accuracy of cCTA, particularly for ruling out CAD. As a known limitation of cCTA a large number of visually significant coronary stenoses are found to be hemodynamically not relevant by invasive fractional flow reserve (FFR). CT-based FFR (CT-FFR) builds on recent advances in computational fluid dynamics and image simulation techniques. Along with CT myocardial perfusion imaging, CT-FFR is a promising approach towards a more accurate estimation of the hemodynamic relevance of coronary artery stenoses. CT-FFR is derived from regular CT datasets without additional image acquisitions, contrast material, or medication. Two CT-FFR techniques can be differentiated. The initial method requires external use of supercomputers and has gained approval for clinical use in the USA. Furthermore, a prototype-software has been introduced which is less computationally demanding via integration of reduced-order models for on-site calculation of CT-FFR. The present article reviews these methods in the context of available study results and meta-analyses. Furthermore, limitations and future concepts of CT-FFR are discussed.

Indexed as

Blood Flow VelocityFractional Flow Reserve, MyocardialAngina, StableComputed Tomography AngiographyCoronary AngiographyEvidence-Based MedicineHumansReproducibility of ResultsSensitivity and SpecificityAngiographyCoronary artery diseaseCoronary stenosisMyocardial perfusion imagingTomography

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.